Determination of the investigational anti-cancer drug 5,6- dimethylxanthenone-4-acetic acid and its acyl glucuronide in Caco-2 monolayers by liquid chromatography with fluorescence detection: Application to transport studies

• Main Authors: Zhou, S., Feng, X., Kestell, P., Baguley, B.C., Paxton, J.W.
• Other Authors: PHARMACY
• Format: Article
• Published: 2014
• Subjects: 5,6-dimethylxanthenone-4-acetic acid; AP; apical; basolateral; BL; CYP; cytochrome P450; dimethyl sulphoxide; DMSO; DMXAA; DMXAA acyl glucuronide; DMXAA-G; Hank's balanced salt solution; HBSS; HEPES; N-[2-hydroxyethyl]piperazine-N′-[4- butanesulfonic acid]
• Online Access: http://scholarbank.nus.edu.sg/handle/10635/105808
• Institution: National University of Singapore

10.1016/j.jchromb.2004.06.009