Discovery of simplified N2-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: Efficient synthetic approaches, biological evaluations and molecular docking studies

Discovery of simplified N2-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: Efficient synthetic approaches, biological evaluations and molecular docking studies

10.1016/j.bmc.2014.01.018

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Bibliographic Details
Main Authors: Venkatesan, G., Paira, P., Cheong, S.L., Vamsikrishna, K., Federico, S., Klotz, K.-N., Spalluto, G., Pastorin, G.
Other Authors: PHARMACY
Format: Article
Published: 2014
Subjects:
Adenosine receptor antagonist
Homology modeling
Molecular docking
Pyrazolo[3,4-d]pyrimidine
Structure affinity relationship
Online Access:http://scholarbank.nus.edu.sg/handle/10635/105841
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Institution: National University of Singapore
Description
Summary:10.1016/j.bmc.2014.01.018

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