Discovery of simplified N2-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: Efficient synthetic approaches, biological evaluations and molecular docking studies

10.1016/j.bmc.2014.01.018

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Main Authors: Venkatesan, G., Paira, P., Cheong, S.L., Vamsikrishna, K., Federico, S., Klotz, K.-N., Spalluto, G., Pastorin, G.
Other Authors: PHARMACY
Format: Article
Published: 2014
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Online Access:http://scholarbank.nus.edu.sg/handle/10635/105841
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Institution: National University of Singapore
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spelling sg-nus-scholar.10635-1058412023-10-30T07:41:06Z Discovery of simplified N2-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: Efficient synthetic approaches, biological evaluations and molecular docking studies Venkatesan, G. Paira, P. Cheong, S.L. Vamsikrishna, K. Federico, S. Klotz, K.-N. Spalluto, G. Pastorin, G. PHARMACY Adenosine receptor antagonist Homology modeling Molecular docking Pyrazolo[3,4-d]pyrimidine Structure affinity relationship 10.1016/j.bmc.2014.01.018 Bioorganic and Medicinal Chemistry 22 5 1751-1765 BMECE 2014-10-29T01:51:28Z 2014-10-29T01:51:28Z 2014-03-01 Article Venkatesan, G., Paira, P., Cheong, S.L., Vamsikrishna, K., Federico, S., Klotz, K.-N., Spalluto, G., Pastorin, G. (2014-03-01). Discovery of simplified N2-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: Efficient synthetic approaches, biological evaluations and molecular docking studies. Bioorganic and Medicinal Chemistry 22 (5) : 1751-1765. ScholarBank@NUS Repository. https://doi.org/10.1016/j.bmc.2014.01.018 09680896 http://scholarbank.nus.edu.sg/handle/10635/105841 000331729500024 Scopus
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic Adenosine receptor antagonist
Homology modeling
Molecular docking
Pyrazolo[3,4-d]pyrimidine
Structure affinity relationship
spellingShingle Adenosine receptor antagonist
Homology modeling
Molecular docking
Pyrazolo[3,4-d]pyrimidine
Structure affinity relationship
Venkatesan, G.
Paira, P.
Cheong, S.L.
Vamsikrishna, K.
Federico, S.
Klotz, K.-N.
Spalluto, G.
Pastorin, G.
Discovery of simplified N2-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: Efficient synthetic approaches, biological evaluations and molecular docking studies
description 10.1016/j.bmc.2014.01.018
author2 PHARMACY
author_facet PHARMACY
Venkatesan, G.
Paira, P.
Cheong, S.L.
Vamsikrishna, K.
Federico, S.
Klotz, K.-N.
Spalluto, G.
Pastorin, G.
format Article
author Venkatesan, G.
Paira, P.
Cheong, S.L.
Vamsikrishna, K.
Federico, S.
Klotz, K.-N.
Spalluto, G.
Pastorin, G.
author_sort Venkatesan, G.
title Discovery of simplified N2-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: Efficient synthetic approaches, biological evaluations and molecular docking studies
title_short Discovery of simplified N2-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: Efficient synthetic approaches, biological evaluations and molecular docking studies
title_full Discovery of simplified N2-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: Efficient synthetic approaches, biological evaluations and molecular docking studies
title_fullStr Discovery of simplified N2-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: Efficient synthetic approaches, biological evaluations and molecular docking studies
title_full_unstemmed Discovery of simplified N2-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: Efficient synthetic approaches, biological evaluations and molecular docking studies
title_sort discovery of simplified n2-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: efficient synthetic approaches, biological evaluations and molecular docking studies
publishDate 2014
url http://scholarbank.nus.edu.sg/handle/10635/105841
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