Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1, 5-a][1,3,5]triazines as thymidine phosphorylase inhibitors

Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1, 5-a][1,3,5]triazines as thymidine phosphorylase inhibitors

10.1016/j.ejmech.2013.10.022

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Bibliographic Details
Main Authors: Sun, L., Li, J., Bera, H., Dolzhenko, A.V., Chiu, G.N.C., Chui, W.K.
Other Authors: PHARMACY
Format: Article
Published: 2014
Subjects:
5-Chlorouracil-linked-pyrazolo[1,5-a][1,3,5]triazines
Fragment-based drug design
Mixed-type enzyme inhibition kinetics
Thymidine phosphorylase inhibitor
Online Access:http://scholarbank.nus.edu.sg/handle/10635/105967
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Institution: National University of Singapore
Description
Summary:10.1016/j.ejmech.2013.10.022

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