Rational design of resorcylic acid lactone analogues as covalent MNK1/2 kinase inhibitors by tuning the reactivity of an enamide Michael acceptor

Rational design of resorcylic acid lactone analogues as covalent MNK1/2 kinase inhibitors by tuning the reactivity of an enamide Michael acceptor

10.1002/cmdc.201300231

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Bibliographic Details
Main Authors: Xu, J., Chen, A., Joy, J., Xavier, V.J., Ong, E.H.Q., Hill, J., Chai, C.L.L.
Other Authors: PHARMACY
Format: Article
Published: 2014
Subjects:
Antitumor agents
Covalent inhibitors
Enamides
Kinases
Michael acceptors
Resorcylic acid lactones
Online Access:http://scholarbank.nus.edu.sg/handle/10635/106292
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Institution: National University of Singapore

Internet

http://scholarbank.nus.edu.sg/handle/10635/106292

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