Rational design of resorcylic acid lactone analogues as covalent MNK1/2 kinase inhibitors by tuning the reactivity of an enamide Michael acceptor

10.1002/cmdc.201300231

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Main Authors: Xu, J., Chen, A., Joy, J., Xavier, V.J., Ong, E.H.Q., Hill, J., Chai, C.L.L.
Other Authors: PHARMACY
Format: Article
Published: 2014
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Online Access:http://scholarbank.nus.edu.sg/handle/10635/106292
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Institution: National University of Singapore
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spelling sg-nus-scholar.10635-1062922023-10-31T07:17:50Z Rational design of resorcylic acid lactone analogues as covalent MNK1/2 kinase inhibitors by tuning the reactivity of an enamide Michael acceptor Xu, J. Chen, A. Joy, J. Xavier, V.J. Ong, E.H.Q. Hill, J. Chai, C.L.L. PHARMACY Antitumor agents Covalent inhibitors Enamides Kinases Michael acceptors Resorcylic acid lactones 10.1002/cmdc.201300231 ChemMedChem 8 9 1483-1494 CHEMG 2014-10-29T01:57:53Z 2014-10-29T01:57:53Z 2013-09 Article Xu, J., Chen, A., Joy, J., Xavier, V.J., Ong, E.H.Q., Hill, J., Chai, C.L.L. (2013-09). Rational design of resorcylic acid lactone analogues as covalent MNK1/2 kinase inhibitors by tuning the reactivity of an enamide Michael acceptor. ChemMedChem 8 (9) : 1483-1494. ScholarBank@NUS Repository. https://doi.org/10.1002/cmdc.201300231 18607179 http://scholarbank.nus.edu.sg/handle/10635/106292 000323541300013 Scopus
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic Antitumor agents
Covalent inhibitors
Enamides
Kinases
Michael acceptors
Resorcylic acid lactones
spellingShingle Antitumor agents
Covalent inhibitors
Enamides
Kinases
Michael acceptors
Resorcylic acid lactones
Xu, J.
Chen, A.
Joy, J.
Xavier, V.J.
Ong, E.H.Q.
Hill, J.
Chai, C.L.L.
Rational design of resorcylic acid lactone analogues as covalent MNK1/2 kinase inhibitors by tuning the reactivity of an enamide Michael acceptor
description 10.1002/cmdc.201300231
author2 PHARMACY
author_facet PHARMACY
Xu, J.
Chen, A.
Joy, J.
Xavier, V.J.
Ong, E.H.Q.
Hill, J.
Chai, C.L.L.
format Article
author Xu, J.
Chen, A.
Joy, J.
Xavier, V.J.
Ong, E.H.Q.
Hill, J.
Chai, C.L.L.
author_sort Xu, J.
title Rational design of resorcylic acid lactone analogues as covalent MNK1/2 kinase inhibitors by tuning the reactivity of an enamide Michael acceptor
title_short Rational design of resorcylic acid lactone analogues as covalent MNK1/2 kinase inhibitors by tuning the reactivity of an enamide Michael acceptor
title_full Rational design of resorcylic acid lactone analogues as covalent MNK1/2 kinase inhibitors by tuning the reactivity of an enamide Michael acceptor
title_fullStr Rational design of resorcylic acid lactone analogues as covalent MNK1/2 kinase inhibitors by tuning the reactivity of an enamide Michael acceptor
title_full_unstemmed Rational design of resorcylic acid lactone analogues as covalent MNK1/2 kinase inhibitors by tuning the reactivity of an enamide Michael acceptor
title_sort rational design of resorcylic acid lactone analogues as covalent mnk1/2 kinase inhibitors by tuning the reactivity of an enamide michael acceptor
publishDate 2014
url http://scholarbank.nus.edu.sg/handle/10635/106292
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