The significance of 2-furyl ring substitution with a 2-(para -substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA3 adenosine receptors antagonists: New insights into structure-affinity relationship and receptor-antagonist recognition

10.1021/jm100049f

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Main Authors:	Cheong, S.L., Dolzhenko, A., Kachler, S., Paoletta, S., Federico, S., Cacciari, B., Klotz, K.-N., Moro, S., Spalluto, G., Pastorin, G.
Other Authors:	PHARMACY
Format:	Article
Published:	2014
Online Access:	http://scholarbank.nus.edu.sg/handle/10635/106452
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-106452
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spelling	sg-nus-scholar.10635-1064522023-10-29T22:18:27Z The significance of 2-furyl ring substitution with a 2-(para -substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA3 adenosine receptors antagonists: New insights into structure-affinity relationship and receptor-antagonist recognition Cheong, S.L. Dolzhenko, A. Kachler, S. Paoletta, S. Federico, S. Cacciari, B. Dolzhenko, A. Klotz, K.-N. Moro, S. Spalluto, G. Pastorin, G. PHARMACY 10.1021/jm100049f Journal of Medicinal Chemistry 53 8 3361-3375 JMCMA 2014-10-29T02:00:13Z 2014-10-29T02:00:13Z 2010-04-22 Article Cheong, S.L., Dolzhenko, A., Kachler, S., Paoletta, S., Federico, S., Cacciari, B., Dolzhenko, A., Klotz, K.-N., Moro, S., Spalluto, G., Pastorin, G. (2010-04-22). The significance of 2-furyl ring substitution with a 2-(para -substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA3 adenosine receptors antagonists: New insights into structure-affinity relationship and receptor-antagonist recognition. Journal of Medicinal Chemistry 53 (8) : 3361-3375. ScholarBank@NUS Repository. https://doi.org/10.1021/jm100049f 00222623 http://scholarbank.nus.edu.sg/handle/10635/106452 000276562400030 Scopus
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
description	10.1021/jm100049f
author2	PHARMACY
author_facet	PHARMACY Cheong, S.L. Dolzhenko, A. Kachler, S. Paoletta, S. Federico, S. Cacciari, B. Dolzhenko, A. Klotz, K.-N. Moro, S. Spalluto, G. Pastorin, G.
format	Article
author	Cheong, S.L. Dolzhenko, A. Kachler, S. Paoletta, S. Federico, S. Cacciari, B. Dolzhenko, A. Klotz, K.-N. Moro, S. Spalluto, G. Pastorin, G.
spellingShingle	Cheong, S.L. Dolzhenko, A. Kachler, S. Paoletta, S. Federico, S. Cacciari, B. Dolzhenko, A. Klotz, K.-N. Moro, S. Spalluto, G. Pastorin, G. The significance of 2-furyl ring substitution with a 2-(para -substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA3 adenosine receptors antagonists: New insights into structure-affinity relationship and receptor-antagonist recognition
author_sort	Cheong, S.L.
title	The significance of 2-furyl ring substitution with a 2-(para -substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA3 adenosine receptors antagonists: New insights into structure-affinity relationship and receptor-antagonist recognition
title_short	The significance of 2-furyl ring substitution with a 2-(para -substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA3 adenosine receptors antagonists: New insights into structure-affinity relationship and receptor-antagonist recognition
title_full	The significance of 2-furyl ring substitution with a 2-(para -substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA3 adenosine receptors antagonists: New insights into structure-affinity relationship and receptor-antagonist recognition
title_fullStr	The significance of 2-furyl ring substitution with a 2-(para -substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA3 adenosine receptors antagonists: New insights into structure-affinity relationship and receptor-antagonist recognition
title_full_unstemmed	The significance of 2-furyl ring substitution with a 2-(para -substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA3 adenosine receptors antagonists: New insights into structure-affinity relationship and receptor-antagonist recognition
title_sort	significance of 2-furyl ring substitution with a 2-(para -substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective ha3 adenosine receptors antagonists: new insights into structure-affinity relationship and receptor-antagonist recognition
publishDate	2014
url	http://scholarbank.nus.edu.sg/handle/10635/106452
_version_	1781788249288605696

The significance of 2-furyl ring substitution with a 2-(para -substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA3 adenosine receptors antagonists: New insights into structure-affinity relationship and receptor-antagonist recognition

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