Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: Conformational selection highlights a new concept in allosteric inhibitor design

10.1074/mcp.M110.004390

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Bibliographic Details
Main Authors: Badireddy, S., Yunfeng, G., Ritchie, M., Akamine, P., Wu, J., Kim, C.W., Taylor, S.S., Qingsong, L., Swaminathan, K., Anand, G.S.
Other Authors: MECHANOBIOLOGY INSTITUTE
Format: Article
Published: 2014
Online Access:http://scholarbank.nus.edu.sg/handle/10635/113125
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Institution: National University of Singapore
Description
Summary:10.1074/mcp.M110.004390