Efficacy and tolerability of rivastigmine patch therapy in patients with mild-to-moderate Alzheimer’s dementia associated with minimal and moderate ischemic white matter hyperintensities: A multicenter prospective open-label clinical trial
10.1371/journal.pone.0182123
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sg-nus-scholar.10635-1611802024-11-10T05:52:50Z Efficacy and tolerability of rivastigmine patch therapy in patients with mild-to-moderate Alzheimer’s dementia associated with minimal and moderate ischemic white matter hyperintensities: A multicenter prospective open-label clinical trial Park K.W. Kim E.-J. Han H.J. Shim Y.S. Kwon J.C. Ku B.D. Park K.H. Yi H.-A. Kim K.K. Yang D.W. Lee H.-W. Kang H. Kwon O.D. Kim S. Lee J.-H. Chung E.J. Park S.-W. Park M.Y. Yoon B. Kim B.C. Seo S.W. Choi S.H. BIOLOGY rivastigmine cholinesterase inhibitor neuroprotective agent rivastigmine abscess aged Alzheimer disease Alzheimer Disease Assessment Scale anorexia Article bradycardia clinical trial dizziness drug dose titration drug efficacy drug tolerability drug withdrawal dyspnea edema epigastric discomfort epigastric pain female fracture headache herpes zoster human intention to treat analysis major clinical study male multicenter study nausea nervous system parameters open study paresthesia prospective study pruritus rash shoulder pain skin irritation treatment outcome upper respiratory tract infection vomiting white matter white matter hyperintensity Alzheimer disease brain diagnostic imaging drug effects middle aged severity of illness index South Korea transdermal patch very elderly white matter Aged Aged, 80 and over Alzheimer Disease Brain Cholinesterase Inhibitors Female Humans Male Middle Aged Neuroprotective Agents Republic of Korea Rivastigmine Severity of Illness Index Transdermal Patch Treatment Outcome White Matter 10.1371/journal.pone.0182123 PLoS ONE 12 8 e0182123 2019-11-01T07:50:13Z 2019-11-01T07:50:13Z 2017 Article Park K.W., Kim E.-J., Han H.J., Shim Y.S., Kwon J.C., Ku B.D., Park K.H., Yi H.-A., Kim K.K., Yang D.W., Lee H.-W., Kang H., Kwon O.D., Kim S., Lee J.-H., Chung E.J., Park S.-W., Park M.Y., Yoon B., Kim B.C., Seo S.W., Choi S.H. (2017). Efficacy and tolerability of rivastigmine patch therapy in patients with mild-to-moderate Alzheimer’s dementia associated with minimal and moderate ischemic white matter hyperintensities: A multicenter prospective open-label clinical trial. PLoS ONE 12 (8) : e0182123. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0182123 19326203 https://scholarbank.nus.edu.sg/handle/10635/161180 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101 |
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rivastigmine cholinesterase inhibitor neuroprotective agent rivastigmine abscess aged Alzheimer disease Alzheimer Disease Assessment Scale anorexia Article bradycardia clinical trial dizziness drug dose titration drug efficacy drug tolerability drug withdrawal dyspnea edema epigastric discomfort epigastric pain female fracture headache herpes zoster human intention to treat analysis major clinical study male multicenter study nausea nervous system parameters open study paresthesia prospective study pruritus rash shoulder pain skin irritation treatment outcome upper respiratory tract infection vomiting white matter white matter hyperintensity Alzheimer disease brain diagnostic imaging drug effects middle aged severity of illness index South Korea transdermal patch very elderly white matter Aged Aged, 80 and over Alzheimer Disease Brain Cholinesterase Inhibitors Female Humans Male Middle Aged Neuroprotective Agents Republic of Korea Rivastigmine Severity of Illness Index Transdermal Patch Treatment Outcome White Matter |
| spellingShingle |
rivastigmine cholinesterase inhibitor neuroprotective agent rivastigmine abscess aged Alzheimer disease Alzheimer Disease Assessment Scale anorexia Article bradycardia clinical trial dizziness drug dose titration drug efficacy drug tolerability drug withdrawal dyspnea edema epigastric discomfort epigastric pain female fracture headache herpes zoster human intention to treat analysis major clinical study male multicenter study nausea nervous system parameters open study paresthesia prospective study pruritus rash shoulder pain skin irritation treatment outcome upper respiratory tract infection vomiting white matter white matter hyperintensity Alzheimer disease brain diagnostic imaging drug effects middle aged severity of illness index South Korea transdermal patch very elderly white matter Aged Aged, 80 and over Alzheimer Disease Brain Cholinesterase Inhibitors Female Humans Male Middle Aged Neuroprotective Agents Republic of Korea Rivastigmine Severity of Illness Index Transdermal Patch Treatment Outcome White Matter Park K.W. Kim E.-J. Han H.J. Shim Y.S. Kwon J.C. Ku B.D. Park K.H. Yi H.-A. Kim K.K. Yang D.W. Lee H.-W. Kang H. Kwon O.D. Kim S. Lee J.-H. Chung E.J. Park S.-W. Park M.Y. Yoon B. Kim B.C. Seo S.W. Choi S.H. Efficacy and tolerability of rivastigmine patch therapy in patients with mild-to-moderate Alzheimer’s dementia associated with minimal and moderate ischemic white matter hyperintensities: A multicenter prospective open-label clinical trial |
| description |
10.1371/journal.pone.0182123 |
| author2 |
BIOLOGY |
| author_facet |
BIOLOGY Park K.W. Kim E.-J. Han H.J. Shim Y.S. Kwon J.C. Ku B.D. Park K.H. Yi H.-A. Kim K.K. Yang D.W. Lee H.-W. Kang H. Kwon O.D. Kim S. Lee J.-H. Chung E.J. Park S.-W. Park M.Y. Yoon B. Kim B.C. Seo S.W. Choi S.H. |
| format |
Article |
| author |
Park K.W. Kim E.-J. Han H.J. Shim Y.S. Kwon J.C. Ku B.D. Park K.H. Yi H.-A. Kim K.K. Yang D.W. Lee H.-W. Kang H. Kwon O.D. Kim S. Lee J.-H. Chung E.J. Park S.-W. Park M.Y. Yoon B. Kim B.C. Seo S.W. Choi S.H. |
| author_sort |
Park K.W. |
| title |
Efficacy and tolerability of rivastigmine patch therapy in patients with mild-to-moderate Alzheimer’s dementia associated with minimal and moderate ischemic white matter hyperintensities: A multicenter prospective open-label clinical trial |
| title_short |
Efficacy and tolerability of rivastigmine patch therapy in patients with mild-to-moderate Alzheimer’s dementia associated with minimal and moderate ischemic white matter hyperintensities: A multicenter prospective open-label clinical trial |
| title_full |
Efficacy and tolerability of rivastigmine patch therapy in patients with mild-to-moderate Alzheimer’s dementia associated with minimal and moderate ischemic white matter hyperintensities: A multicenter prospective open-label clinical trial |
| title_fullStr |
Efficacy and tolerability of rivastigmine patch therapy in patients with mild-to-moderate Alzheimer’s dementia associated with minimal and moderate ischemic white matter hyperintensities: A multicenter prospective open-label clinical trial |
| title_full_unstemmed |
Efficacy and tolerability of rivastigmine patch therapy in patients with mild-to-moderate Alzheimer’s dementia associated with minimal and moderate ischemic white matter hyperintensities: A multicenter prospective open-label clinical trial |
| title_sort |
efficacy and tolerability of rivastigmine patch therapy in patients with mild-to-moderate alzheimer’s dementia associated with minimal and moderate ischemic white matter hyperintensities: a multicenter prospective open-label clinical trial |
| publishDate |
2019 |
| url |
https://scholarbank.nus.edu.sg/handle/10635/161180 |
| _version_ |
1821194832098361344 |