An integrative analysis of tissue-specific transcriptomic and metabolomic responses to short-term dietary methionine restriction in mice

10.1371/journal.pone.0177513

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Main Authors: Ghosh S., Forney L.A., Wanders D., Stone K.P., Gettys T.W.
Other Authors: DUKE-NUS MEDICAL SCHOOL
Format: Article
Published: 2019
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/161194
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spelling sg-nus-scholar.10635-1611942023-08-04T09:08:31Z An integrative analysis of tissue-specific transcriptomic and metabolomic responses to short-term dietary methionine restriction in mice Ghosh S. Forney L.A. Wanders D. Stone K.P. Gettys T.W. DUKE-NUS MEDICAL SCHOOL 2 aminobutyrate butyric acid derivative cysteine glutamic acid glutathione methionine transcription factor transcription factor NFE2L2 unclassified drug methionine transcriptome adipose tissue animal experiment animal tissue Article citric acid cycle controlled study fatty acid oxidation fatty acid transport inguinal region male metabolic disorder metabolomics mouse nonhuman oxidation reduction reaction oxidative phosphorylation phenotype protein restriction systems biology tissue specificity transcriptomics upregulation animal antibody specificity cluster analysis gene expression profiling gene regulatory network genetics liver metabolism metabolome procedures protein restriction Adipose Tissue Animals Cluster Analysis Diet, Protein-Restricted Gene Expression Profiling Gene Regulatory Networks Liver Male Metabolic Networks and Pathways Metabolome Metabolomics Methionine Mice Organ Specificity Transcriptome 10.1371/journal.pone.0177513 PLoS ONE 12 5 e0177513 2019-11-01T07:53:00Z 2019-11-01T07:53:00Z 2017 Article Ghosh S., Forney L.A., Wanders D., Stone K.P., Gettys T.W. (2017). An integrative analysis of tissue-specific transcriptomic and metabolomic responses to short-term dietary methionine restriction in mice. PLoS ONE 12 (5) : e0177513. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0177513 19326203 https://scholarbank.nus.edu.sg/handle/10635/161194 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic 2 aminobutyrate
butyric acid derivative
cysteine
glutamic acid
glutathione
methionine
transcription factor
transcription factor NFE2L2
unclassified drug
methionine
transcriptome
adipose tissue
animal experiment
animal tissue
Article
citric acid cycle
controlled study
fatty acid oxidation
fatty acid transport
inguinal region
male
metabolic disorder
metabolomics
mouse
nonhuman
oxidation reduction reaction
oxidative phosphorylation
phenotype
protein restriction
systems biology
tissue specificity
transcriptomics
upregulation
animal
antibody specificity
cluster analysis
gene expression profiling
gene regulatory network
genetics
liver
metabolism
metabolome
procedures
protein restriction
Adipose Tissue
Animals
Cluster Analysis
Diet, Protein-Restricted
Gene Expression Profiling
Gene Regulatory Networks
Liver
Male
Metabolic Networks and Pathways
Metabolome
Metabolomics
Methionine
Mice
Organ Specificity
Transcriptome
spellingShingle 2 aminobutyrate
butyric acid derivative
cysteine
glutamic acid
glutathione
methionine
transcription factor
transcription factor NFE2L2
unclassified drug
methionine
transcriptome
adipose tissue
animal experiment
animal tissue
Article
citric acid cycle
controlled study
fatty acid oxidation
fatty acid transport
inguinal region
male
metabolic disorder
metabolomics
mouse
nonhuman
oxidation reduction reaction
oxidative phosphorylation
phenotype
protein restriction
systems biology
tissue specificity
transcriptomics
upregulation
animal
antibody specificity
cluster analysis
gene expression profiling
gene regulatory network
genetics
liver
metabolism
metabolome
procedures
protein restriction
Adipose Tissue
Animals
Cluster Analysis
Diet, Protein-Restricted
Gene Expression Profiling
Gene Regulatory Networks
Liver
Male
Metabolic Networks and Pathways
Metabolome
Metabolomics
Methionine
Mice
Organ Specificity
Transcriptome
Ghosh S.
Forney L.A.
Wanders D.
Stone K.P.
Gettys T.W.
An integrative analysis of tissue-specific transcriptomic and metabolomic responses to short-term dietary methionine restriction in mice
description 10.1371/journal.pone.0177513
author2 DUKE-NUS MEDICAL SCHOOL
author_facet DUKE-NUS MEDICAL SCHOOL
Ghosh S.
Forney L.A.
Wanders D.
Stone K.P.
Gettys T.W.
format Article
author Ghosh S.
Forney L.A.
Wanders D.
Stone K.P.
Gettys T.W.
author_sort Ghosh S.
title An integrative analysis of tissue-specific transcriptomic and metabolomic responses to short-term dietary methionine restriction in mice
title_short An integrative analysis of tissue-specific transcriptomic and metabolomic responses to short-term dietary methionine restriction in mice
title_full An integrative analysis of tissue-specific transcriptomic and metabolomic responses to short-term dietary methionine restriction in mice
title_fullStr An integrative analysis of tissue-specific transcriptomic and metabolomic responses to short-term dietary methionine restriction in mice
title_full_unstemmed An integrative analysis of tissue-specific transcriptomic and metabolomic responses to short-term dietary methionine restriction in mice
title_sort integrative analysis of tissue-specific transcriptomic and metabolomic responses to short-term dietary methionine restriction in mice
publishDate 2019
url https://scholarbank.nus.edu.sg/handle/10635/161194
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