An integrative analysis of tissue-specific transcriptomic and metabolomic responses to short-term dietary methionine restriction in mice

• Main Authors: Ghosh S., Forney L.A., Wanders D., Stone K.P., Gettys T.W.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2019
• Subjects: 2 aminobutyrate; butyric acid derivative; cysteine; glutamic acid; glutathione; methionine; transcription factor; transcription factor NFE2L2; unclassified drug; transcriptome; adipose tissue; animal experiment; animal tissue; Article; citric acid cycle; controlled study; fatty acid oxidation; fatty acid transport; inguinal region; male; metabolic disorder; metabolomics; mouse; nonhuman; oxidation reduction reaction; oxidative phosphorylation; phenotype; protein restriction; systems biology; tissue specificity; transcriptomics; upregulation; animal; antibody specificity; cluster analysis; gene expression profiling; gene regulatory network; genetics; liver; metabolism; metabolome; procedures; Adipose Tissue; Animals; Cluster Analysis; Diet, Protein-Restricted; Gene Expression Profiling; Gene Regulatory Networks; Liver; Male; Metabolic Networks and Pathways; Metabolome; Metabolomics; Methionine; Mice; Organ Specificity; Transcriptome
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161194
• Institution: National University of Singapore

10.1371/journal.pone.0177513