Notch1 deficiency decreases hepatic lipid accumulation by induction of fatty acid oxidation

• Main Authors: Song, N.-J, Yun, U.J, Yang, S, Wu, C, Seo, C.-R, Gwon, A.-R, Baik, S.-H, Choi, Y, Choi, B.Y, Bahn, G, Kim, S, Kwon, S.-M, Park, J.S, Baek, S.H, Park, T.J, Yoon, K, Kim, B.-J, Mattson, M.P, Lee, S.-J, Jo, D.-G, Park, K.W
• Other Authors: PHYSIOLOGY
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: fatty acid; Notch1 receptor; adipocyte; adverse effects; animal; cell line; deficiency; diet; drug effects; fatty liver; gene silencing; genetics; human; insulin resistance; lipid metabolism; liver; metabolism; mouse; obesity; oxidation reduction reaction; oxidative stress; pathology; RNA interference; signal transduction; Adipocytes; Animals; Cell Line; Diet; Fatty Acids; Fatty Liver; Gene Knockdown Techniques; Humans; Insulin Resistance; Lipid Metabolism; Liver; Mice; Obesity; Oxidation-Reduction; Oxidative Stress; Receptor, Notch1; RNA Interference; Signal Transduction
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/182514
• Institution: National University of Singapore

10.1038/srep19377