A Single Amino Acid Substitution in the Core Protein of West Nile Virus Increases Resistance to Acidotropic Compounds

A Single Amino Acid Substitution in the Core Protein of West Nile Virus Increases Resistance to Acidotropic Compounds

10.1371/journal.pone.0069479

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Bibliographic Details
Main Authors:	Martín-Acebes M.A., Blázquez A.-B., de Oya N.J., Escribano-Romero E., Shi P.-Y., Saiz J.-C.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2019
Subjects:	amino acid ammonium chloride concanamycin A core protein glutamine lysine virus protein acidification amino acid substitution animal experiment article controlled study endosome female genetic stability mouse nonhuman nucleotide sequence pH phenotype trans Golgi network virion virus entry virus envelope West Nile flavivirus Amino Acid Substitution Ammonium Chloride Analysis of Variance Animals Blotting, Western Cercopithecus aethiops Cricetinae Drug Resistance, Viral Fluorescent Antibody Technique Hydrogen-Ion Concentration Macrolides Mice Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction Vero Cells Viral Core Proteins Virulence West Nile virus
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161290
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Institution:	National University of Singapore

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