The Bile Acid Sensor FXR Is Required for Immune-Regulatory Activities of TLR-9 in Intestinal Inflammation

• Main Authors: Renga B., Mencarelli A., Cipriani S., D'Amore C., Carino A., Bruno A., Francisci D., Zampella A., Distrutti E., Fiorucci S.
• Other Authors: DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
• Format: Article
• Published: 2019
• Subjects: farnesoid X receptor; interferon regulatory factor 7; myeloid differentiation factor 88; toll like receptor 2; toll like receptor 3; toll like receptor 4; toll like receptor 5; toll like receptor 6; toll like receptor 7; toll like receptor 8; toll like receptor 9; tumor necrosis factor alpha; animal cell; animal experiment; animal model; animal tissue; article; cell activation; controlled study; enteritis; farnesoid X receptor gene; gene expression; human; human cell; immune response; immunoregulation; male; mouse; nonhuman; promoter region; protein expression; protein function; protein protein interaction; receptor upregulation; signal transduction; Animals; Cells, Cultured; Colitis; Gene Expression Regulation; Humans; Immunity, Innate; Inflammation; Interferon Regulatory Factor-7; Intestines; Male; Mice; Mice, Knockout; Monocytes; Myeloid Differentiation Factor 88; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Toll-Like Receptor 9; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha; Mus
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161348
• Institution: National University of Singapore

10.1371/journal.pone.0054472