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Proteasome inhibition promotes Parkin-Ubc13 interaction and lysine 63-linked ubiquitination.

Proteasome inhibition promotes Parkin-Ubc13 interaction and lysine 63-linked ubiquitination.

10.1371/journal.pone.0073235

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Bibliographic Details
Main Authors: Lim G.G., Neurodegeneration Research Laboratory National Neuroscience Institute, Chew K.C., Ng X.H., Henry-Basil A., Sim R.W., Tan J.M., Chai C.
Other Authors: PHYSIOLOGY
Format: Article
Published: 2019
Subjects:
carrier protein
lysine
nerve protein
parkin
proteasome
proteasome inhibitor
protein binding
SNCAIP protein, human
UBE2N protein, human
ubiquitin conjugating enzyme
ubiquitin protein ligase
autophagy
drug effects
genetics
HEK293 cell line
homeostasis
human
metabolism
mutation
protein degradation
protein transport
ubiquitination
Autophagy
Carrier Proteins
HEK293 Cells
Homeostasis
Humans
Lysine
Mutation
Nerve Tissue Proteins
Proteasome Endopeptidase Complex
Proteasome Inhibitors
Protein Binding
Protein Transport
Proteolysis
Ubiquitin-Conjugating Enzymes
Ubiquitin-Protein Ligases
Ubiquitination
Online Access:https://scholarbank.nus.edu.sg/handle/10635/161353
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https://scholarbank.nus.edu.sg/handle/10635/161353

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