Intestinal cell barrier function in vitro is severely compromised by keratin 8 and 18 mutations identified in patients with inflammatory bowel disease
10.1371/journal.pone.0099398
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sg-nus-scholar.10635-1614052024-04-03T07:38:17Z Intestinal cell barrier function in vitro is severely compromised by keratin 8 and 18 mutations identified in patients with inflammatory bowel disease Zupancic T. Stojan J. Lane E.B. Komel R. Bedina-Zavec A. Liovic M. PATHOLOGY claudin 4 cytokeratin 18 cytokeratin 8 protein ZO1 cell extract claudin 4 cytokeratin 18 cytokeratin 8 protein ZO1 amino acid substitution article cell function cell membrane permeability controlled study cytokeratin 18 gene cytokeratin 8 gene dissociation constant gene mutation genetic association growth rate heat stress human human cell in vitro study inflammatory bowel disease intestine cell molecular model permeability barrier protein localization cell proliferation chemical structure genetics heat shock response hydrogen bond inflammatory bowel disease intestine kinetics metabolism mutation pathology protein multimerization protein tertiary structure tumor cell line Western blotting Blotting, Western Cell Extracts Cell Line, Tumor Cell Membrane Permeability Cell Proliferation Claudin-4 Heat-Shock Response Humans Hydrogen Bonding Inflammatory Bowel Diseases Intestines Keratin-18 Keratin-8 Kinetics Models, Molecular Mutation Protein Multimerization Protein Structure, Tertiary Zonula Occludens-1 Protein 10.1371/journal.pone.0099398 PLoS ONE 9 6 e99398 2019-11-05T00:36:17Z 2019-11-05T00:36:17Z 2014 Article Zupancic T., Stojan J., Lane E.B., Komel R., Bedina-Zavec A., Liovic M. (2014). Intestinal cell barrier function in vitro is severely compromised by keratin 8 and 18 mutations identified in patients with inflammatory bowel disease. PLoS ONE 9 (6) : e99398. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0099398 1932-6203 https://scholarbank.nus.edu.sg/handle/10635/161405 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101 |
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claudin 4 cytokeratin 18 cytokeratin 8 protein ZO1 cell extract claudin 4 cytokeratin 18 cytokeratin 8 protein ZO1 amino acid substitution article cell function cell membrane permeability controlled study cytokeratin 18 gene cytokeratin 8 gene dissociation constant gene mutation genetic association growth rate heat stress human human cell in vitro study inflammatory bowel disease intestine cell molecular model permeability barrier protein localization cell proliferation chemical structure genetics heat shock response hydrogen bond inflammatory bowel disease intestine kinetics metabolism mutation pathology protein multimerization protein tertiary structure tumor cell line Western blotting Blotting, Western Cell Extracts Cell Line, Tumor Cell Membrane Permeability Cell Proliferation Claudin-4 Heat-Shock Response Humans Hydrogen Bonding Inflammatory Bowel Diseases Intestines Keratin-18 Keratin-8 Kinetics Models, Molecular Mutation Protein Multimerization Protein Structure, Tertiary Zonula Occludens-1 Protein |
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claudin 4 cytokeratin 18 cytokeratin 8 protein ZO1 cell extract claudin 4 cytokeratin 18 cytokeratin 8 protein ZO1 amino acid substitution article cell function cell membrane permeability controlled study cytokeratin 18 gene cytokeratin 8 gene dissociation constant gene mutation genetic association growth rate heat stress human human cell in vitro study inflammatory bowel disease intestine cell molecular model permeability barrier protein localization cell proliferation chemical structure genetics heat shock response hydrogen bond inflammatory bowel disease intestine kinetics metabolism mutation pathology protein multimerization protein tertiary structure tumor cell line Western blotting Blotting, Western Cell Extracts Cell Line, Tumor Cell Membrane Permeability Cell Proliferation Claudin-4 Heat-Shock Response Humans Hydrogen Bonding Inflammatory Bowel Diseases Intestines Keratin-18 Keratin-8 Kinetics Models, Molecular Mutation Protein Multimerization Protein Structure, Tertiary Zonula Occludens-1 Protein Zupancic T. Stojan J. Lane E.B. Komel R. Bedina-Zavec A. Liovic M. Intestinal cell barrier function in vitro is severely compromised by keratin 8 and 18 mutations identified in patients with inflammatory bowel disease |
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10.1371/journal.pone.0099398 |
author2 |
PATHOLOGY |
author_facet |
PATHOLOGY Zupancic T. Stojan J. Lane E.B. Komel R. Bedina-Zavec A. Liovic M. |
format |
Article |
author |
Zupancic T. Stojan J. Lane E.B. Komel R. Bedina-Zavec A. Liovic M. |
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Zupancic T. |
title |
Intestinal cell barrier function in vitro is severely compromised by keratin 8 and 18 mutations identified in patients with inflammatory bowel disease |
title_short |
Intestinal cell barrier function in vitro is severely compromised by keratin 8 and 18 mutations identified in patients with inflammatory bowel disease |
title_full |
Intestinal cell barrier function in vitro is severely compromised by keratin 8 and 18 mutations identified in patients with inflammatory bowel disease |
title_fullStr |
Intestinal cell barrier function in vitro is severely compromised by keratin 8 and 18 mutations identified in patients with inflammatory bowel disease |
title_full_unstemmed |
Intestinal cell barrier function in vitro is severely compromised by keratin 8 and 18 mutations identified in patients with inflammatory bowel disease |
title_sort |
intestinal cell barrier function in vitro is severely compromised by keratin 8 and 18 mutations identified in patients with inflammatory bowel disease |
publishDate |
2019 |
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https://scholarbank.nus.edu.sg/handle/10635/161405 |
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1795374101013987328 |