Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway

10.1371/journal.pone.0085318

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Main Authors:	Lu J.-W., Liao C.-Y., Yang W.-Y., Lin Y.-M., Jin S.-L.C., Wang H.-D., Yuh C.-H.
Other Authors:	BIOLOGICAL SCIENCES
Format:	Article
Published:	2019
Subjects:	activating transcription factor 6 endothelin 1 fluorescent dye glycogen mCherry microRNA 1 protein IRE1 protein kinase protein kinase B protein PERK RNA unclassified drug X box binding protein 1 adult animal cell animal experiment animal model animal tissue article bile duct dilatation cancer growth cancer patient cell culture cell migration cell proliferation controlled study embryo fatty liver gene expression regulation glycogen metabolism in vitro study liver cancer liver carcinogenesis liver fibrosis liver hyperplasia nonhuman nucleotide sequence protein analysis protein expression protein function RNA splicing signal transduction tissue specificity transgenic animal unfolded protein response upregulation xenotransplantation zebra fish Animals Carcinoma, Hepatocellular Cell Cycle Cell Movement Cell Proliferation Endothelin-1 Fatty Liver Gene Expression HEK293 Cells Humans Liver Cirrhosis Liver Neoplasms MicroRNAs Phosphatidylinositol 3-Kinases Protein Kinase Inhibitors Proto-Oncogene Proteins c-akt Unfolded Protein Response Zebrafish Zebrafish Proteins
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161437
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1614372024-04-03T10:36:50Z Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway Lu J.-W. Liao C.-Y. Yang W.-Y. Lin Y.-M. Jin S.-L.C. Wang H.-D. Yuh C.-H. BIOLOGICAL SCIENCES activating transcription factor 6 endothelin 1 fluorescent dye glycogen mCherry microRNA 1 protein IRE1 protein kinase protein kinase B protein PERK RNA unclassified drug X box binding protein 1 adult animal cell animal experiment animal model animal tissue article bile duct dilatation cancer growth cancer patient cell culture cell migration cell proliferation controlled study embryo fatty liver gene expression regulation glycogen metabolism in vitro study liver cancer liver carcinogenesis liver fibrosis liver hyperplasia nonhuman nucleotide sequence protein analysis protein expression protein function RNA splicing signal transduction tissue specificity transgenic animal unfolded protein response upregulation xenotransplantation zebra fish Animals Carcinoma, Hepatocellular Cell Cycle Cell Movement Cell Proliferation Endothelin-1 Fatty Liver Gene Expression HEK293 Cells Humans Liver Cirrhosis Liver Neoplasms MicroRNAs Phosphatidylinositol 3-Kinases Protein Kinase Inhibitors Proto-Oncogene Proteins c-akt Unfolded Protein Response Zebrafish Zebrafish Proteins 10.1371/journal.pone.0085318 PLoS ONE 9 1 e85318 2019-11-05T02:05:10Z 2019-11-05T02:05:10Z 2014 Article Lu J.-W., Liao C.-Y., Yang W.-Y., Lin Y.-M., Jin S.-L.C., Wang H.-D., Yuh C.-H. (2014). Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway. PLoS ONE 9 (1) : e85318. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0085318 1932-6203 https://scholarbank.nus.edu.sg/handle/10635/161437 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	activating transcription factor 6 endothelin 1 fluorescent dye glycogen mCherry microRNA 1 protein IRE1 protein kinase protein kinase B protein PERK RNA unclassified drug X box binding protein 1 adult animal cell animal experiment animal model animal tissue article bile duct dilatation cancer growth cancer patient cell culture cell migration cell proliferation controlled study embryo fatty liver gene expression regulation glycogen metabolism in vitro study liver cancer liver carcinogenesis liver fibrosis liver hyperplasia nonhuman nucleotide sequence protein analysis protein expression protein function RNA splicing signal transduction tissue specificity transgenic animal unfolded protein response upregulation xenotransplantation zebra fish Animals Carcinoma, Hepatocellular Cell Cycle Cell Movement Cell Proliferation Endothelin-1 Fatty Liver Gene Expression HEK293 Cells Humans Liver Cirrhosis Liver Neoplasms MicroRNAs Phosphatidylinositol 3-Kinases Protein Kinase Inhibitors Proto-Oncogene Proteins c-akt Unfolded Protein Response Zebrafish Zebrafish Proteins
spellingShingle	activating transcription factor 6 endothelin 1 fluorescent dye glycogen mCherry microRNA 1 protein IRE1 protein kinase protein kinase B protein PERK RNA unclassified drug X box binding protein 1 adult animal cell animal experiment animal model animal tissue article bile duct dilatation cancer growth cancer patient cell culture cell migration cell proliferation controlled study embryo fatty liver gene expression regulation glycogen metabolism in vitro study liver cancer liver carcinogenesis liver fibrosis liver hyperplasia nonhuman nucleotide sequence protein analysis protein expression protein function RNA splicing signal transduction tissue specificity transgenic animal unfolded protein response upregulation xenotransplantation zebra fish Animals Carcinoma, Hepatocellular Cell Cycle Cell Movement Cell Proliferation Endothelin-1 Fatty Liver Gene Expression HEK293 Cells Humans Liver Cirrhosis Liver Neoplasms MicroRNAs Phosphatidylinositol 3-Kinases Protein Kinase Inhibitors Proto-Oncogene Proteins c-akt Unfolded Protein Response Zebrafish Zebrafish Proteins Lu J.-W. Liao C.-Y. Yang W.-Y. Lin Y.-M. Jin S.-L.C. Wang H.-D. Yuh C.-H. Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway
description	10.1371/journal.pone.0085318
author2	BIOLOGICAL SCIENCES
author_facet	BIOLOGICAL SCIENCES Lu J.-W. Liao C.-Y. Yang W.-Y. Lin Y.-M. Jin S.-L.C. Wang H.-D. Yuh C.-H.
format	Article
author	Lu J.-W. Liao C.-Y. Yang W.-Y. Lin Y.-M. Jin S.-L.C. Wang H.-D. Yuh C.-H.
author_sort	Lu J.-W.
title	Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway
title_short	Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway
title_full	Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway
title_fullStr	Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway
title_full_unstemmed	Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway
title_sort	overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the akt pathway
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161437
_version_	1795374102441099264

Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway

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