Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish

10.1371/journal.pone.0076951

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Main Authors:	Lu J.-W., Yang W.-Y., Tsai S.-M., Lin Y.-M., Chang P.-H., Chen J.-R., Wang H.-D., Wu J.-L., Jin S.-L.C., Yuh C.-H.
Other Authors:	BIOLOGICAL SCIENCES
Format:	Article
Published:	2019
Subjects:	glycogen hepatitis B virus X antigen mitogen activated protein kinase Myc protein protein kinase B protein p53 protein tyrosine kinase stress activated protein kinase 1 unclassified drug vasculotropin virus antigen animal experiment animal model animal tissue article cancer growth cancer staging controlled study drug screening enzyme activation enzyme phosphorylation gene function gene mutation glycogen metabolism in vivo study lipid metabolism lipogenesis liver carcinogenesis liver cell carcinoma liver hyperplasia nonhuman protein analysis protein expression signal transduction tissue specificity transgenic animal upregulation zebra fish Animals Animals, Genetically Modified Apoptosis Carcinogenesis Carcinoma, Hepatocellular Cell Cycle Enzyme Activation Fibrosis Gene Expression Glycogen Humans Hyperplasia Lipogenesis Liver Liver Neoplasms Mutation Neoplasm Metastasis Organ Specificity Proliferating Cell Nuclear Antigen Recombinant Fusion Proteins Signal Transduction src-Family Kinases Trans-Activators Tumor Markers, Biological Tumor Suppressor Protein p53 Zebrafish
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161462
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1614622024-04-03T10:36:50Z Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish Lu J.-W. Yang W.-Y. Tsai S.-M. Lin Y.-M. Chang P.-H. Chen J.-R. Wang H.-D. Wu J.-L. Jin S.-L.C. Yuh C.-H. BIOLOGICAL SCIENCES glycogen hepatitis B virus X antigen mitogen activated protein kinase Myc protein protein kinase B protein p53 protein tyrosine kinase stress activated protein kinase 1 unclassified drug vasculotropin virus antigen animal experiment animal model animal tissue article cancer growth cancer staging controlled study drug screening enzyme activation enzyme phosphorylation gene function gene mutation glycogen metabolism in vivo study lipid metabolism lipogenesis liver carcinogenesis liver cell carcinoma liver hyperplasia nonhuman protein analysis protein expression signal transduction tissue specificity transgenic animal upregulation zebra fish Animals Animals, Genetically Modified Apoptosis Carcinogenesis Carcinoma, Hepatocellular Cell Cycle Enzyme Activation Fibrosis Gene Expression Glycogen Humans Hyperplasia Lipogenesis Liver Liver Neoplasms Mutation Neoplasm Metastasis Organ Specificity Proliferating Cell Nuclear Antigen Recombinant Fusion Proteins Signal Transduction src-Family Kinases Trans-Activators Tumor Markers, Biological Tumor Suppressor Protein p53 Zebrafish 10.1371/journal.pone.0076951 PLoS ONE 8 10 e76951 2019-11-05T02:11:53Z 2019-11-05T02:11:53Z 2013 Article Lu J.-W., Yang W.-Y., Tsai S.-M., Lin Y.-M., Chang P.-H., Chen J.-R., Wang H.-D., Wu J.-L., Jin S.-L.C., Yuh C.-H. (2013). Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish. PLoS ONE 8 (10) : e76951. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0076951 1932-6203 https://scholarbank.nus.edu.sg/handle/10635/161462 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	glycogen hepatitis B virus X antigen mitogen activated protein kinase Myc protein protein kinase B protein p53 protein tyrosine kinase stress activated protein kinase 1 unclassified drug vasculotropin virus antigen animal experiment animal model animal tissue article cancer growth cancer staging controlled study drug screening enzyme activation enzyme phosphorylation gene function gene mutation glycogen metabolism in vivo study lipid metabolism lipogenesis liver carcinogenesis liver cell carcinoma liver hyperplasia nonhuman protein analysis protein expression signal transduction tissue specificity transgenic animal upregulation zebra fish Animals Animals, Genetically Modified Apoptosis Carcinogenesis Carcinoma, Hepatocellular Cell Cycle Enzyme Activation Fibrosis Gene Expression Glycogen Humans Hyperplasia Lipogenesis Liver Liver Neoplasms Mutation Neoplasm Metastasis Organ Specificity Proliferating Cell Nuclear Antigen Recombinant Fusion Proteins Signal Transduction src-Family Kinases Trans-Activators Tumor Markers, Biological Tumor Suppressor Protein p53 Zebrafish
spellingShingle	glycogen hepatitis B virus X antigen mitogen activated protein kinase Myc protein protein kinase B protein p53 protein tyrosine kinase stress activated protein kinase 1 unclassified drug vasculotropin virus antigen animal experiment animal model animal tissue article cancer growth cancer staging controlled study drug screening enzyme activation enzyme phosphorylation gene function gene mutation glycogen metabolism in vivo study lipid metabolism lipogenesis liver carcinogenesis liver cell carcinoma liver hyperplasia nonhuman protein analysis protein expression signal transduction tissue specificity transgenic animal upregulation zebra fish Animals Animals, Genetically Modified Apoptosis Carcinogenesis Carcinoma, Hepatocellular Cell Cycle Enzyme Activation Fibrosis Gene Expression Glycogen Humans Hyperplasia Lipogenesis Liver Liver Neoplasms Mutation Neoplasm Metastasis Organ Specificity Proliferating Cell Nuclear Antigen Recombinant Fusion Proteins Signal Transduction src-Family Kinases Trans-Activators Tumor Markers, Biological Tumor Suppressor Protein p53 Zebrafish Lu J.-W. Yang W.-Y. Tsai S.-M. Lin Y.-M. Chang P.-H. Chen J.-R. Wang H.-D. Wu J.-L. Jin S.-L.C. Yuh C.-H. Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish
description	10.1371/journal.pone.0076951
author2	BIOLOGICAL SCIENCES
author_facet	BIOLOGICAL SCIENCES Lu J.-W. Yang W.-Y. Tsai S.-M. Lin Y.-M. Chang P.-H. Chen J.-R. Wang H.-D. Wu J.-L. Jin S.-L.C. Yuh C.-H.
format	Article
author	Lu J.-W. Yang W.-Y. Tsai S.-M. Lin Y.-M. Chang P.-H. Chen J.-R. Wang H.-D. Wu J.-L. Jin S.-L.C. Yuh C.-H.
author_sort	Lu J.-W.
title	Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish
title_short	Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish
title_full	Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish
title_fullStr	Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish
title_full_unstemmed	Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish
title_sort	liver-specific expressions of hbx and src in the p53 mutant trigger hepatocarcinogenesis in zebrafish
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161462
_version_	1795374102627745792

Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish

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