Using an adenosine triphosphate bioluminescent assay to determine effective antibiotic combinations against carbapenem-resistant gram negative bacteria within 24 hours

10.1371/journal.pone.0140446

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Main Authors:	Cai Y., Leck H., Lim T.P., Teo J., Lee W., Hsu L.Y., Koh T.H., Tan T.T., Tan T.-Y., Kwa A.L.-H.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2019
Subjects:	adenosine triphosphate carbapenem antiinfective agent carbapenem derivative Acinetobacter baumannii antibiotic resistance Article bacterial count bacterial strain bioluminescence colony forming unit concentration (parameters) controlled study Gram negative bacterium Klebsiella pneumoniae measurement accuracy nonhuman prospective study Pseudomonas aeruginosa receiver operating characteristic sensitivity and specificity validation process dose response drug effects luminescence metabolism microbial sensitivity test multidrug resistance procedures reproducibility Adenosine Triphosphate Anti-Bacterial Agents Carbapenems Colony Count, Microbial Dose-Response Relationship, Drug Drug Resistance, Multiple, Bacterial Gram-Negative Bacteria Luminescent Measurements Microbial Sensitivity Tests Reproducibility of Results ROC Curve
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161485
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1614852023-10-31T09:18:57Z Using an adenosine triphosphate bioluminescent assay to determine effective antibiotic combinations against carbapenem-resistant gram negative bacteria within 24 hours Cai Y. Leck H. Lim T.P. Teo J. Lee W. Hsu L.Y. Koh T.H. Tan T.T. Tan T.-Y. Kwa A.L.-H. DUKE-NUS MEDICAL SCHOOL NUSHS PROJECT SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH adenosine triphosphate carbapenem adenosine triphosphate antiinfective agent carbapenem derivative Acinetobacter baumannii antibiotic resistance Article bacterial count bacterial strain bioluminescence colony forming unit concentration (parameters) controlled study Gram negative bacterium Klebsiella pneumoniae measurement accuracy nonhuman prospective study Pseudomonas aeruginosa receiver operating characteristic sensitivity and specificity validation process dose response drug effects Gram negative bacterium luminescence metabolism microbial sensitivity test multidrug resistance procedures reproducibility Adenosine Triphosphate Anti-Bacterial Agents Carbapenems Colony Count, Microbial Dose-Response Relationship, Drug Drug Resistance, Multiple, Bacterial Gram-Negative Bacteria Luminescent Measurements Microbial Sensitivity Tests Reproducibility of Results ROC Curve 10.1371/journal.pone.0140446 PLoS ONE 10 10 e0140446 2019-11-06T01:26:25Z 2019-11-06T01:26:25Z 2015 Article Cai Y., Leck H., Lim T.P., Teo J., Lee W., Hsu L.Y., Koh T.H., Tan T.T., Tan T.-Y., Kwa A.L.-H. (2015). Using an adenosine triphosphate bioluminescent assay to determine effective antibiotic combinations against carbapenem-resistant gram negative bacteria within 24 hours. PLoS ONE 10 (10) : e0140446. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0140446 19326203 https://scholarbank.nus.edu.sg/handle/10635/161485 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	adenosine triphosphate carbapenem adenosine triphosphate antiinfective agent carbapenem derivative Acinetobacter baumannii antibiotic resistance Article bacterial count bacterial strain bioluminescence colony forming unit concentration (parameters) controlled study Gram negative bacterium Klebsiella pneumoniae measurement accuracy nonhuman prospective study Pseudomonas aeruginosa receiver operating characteristic sensitivity and specificity validation process dose response drug effects Gram negative bacterium luminescence metabolism microbial sensitivity test multidrug resistance procedures reproducibility Adenosine Triphosphate Anti-Bacterial Agents Carbapenems Colony Count, Microbial Dose-Response Relationship, Drug Drug Resistance, Multiple, Bacterial Gram-Negative Bacteria Luminescent Measurements Microbial Sensitivity Tests Reproducibility of Results ROC Curve
spellingShingle	adenosine triphosphate carbapenem adenosine triphosphate antiinfective agent carbapenem derivative Acinetobacter baumannii antibiotic resistance Article bacterial count bacterial strain bioluminescence colony forming unit concentration (parameters) controlled study Gram negative bacterium Klebsiella pneumoniae measurement accuracy nonhuman prospective study Pseudomonas aeruginosa receiver operating characteristic sensitivity and specificity validation process dose response drug effects Gram negative bacterium luminescence metabolism microbial sensitivity test multidrug resistance procedures reproducibility Adenosine Triphosphate Anti-Bacterial Agents Carbapenems Colony Count, Microbial Dose-Response Relationship, Drug Drug Resistance, Multiple, Bacterial Gram-Negative Bacteria Luminescent Measurements Microbial Sensitivity Tests Reproducibility of Results ROC Curve Cai Y. Leck H. Lim T.P. Teo J. Lee W. Hsu L.Y. Koh T.H. Tan T.T. Tan T.-Y. Kwa A.L.-H. Using an adenosine triphosphate bioluminescent assay to determine effective antibiotic combinations against carbapenem-resistant gram negative bacteria within 24 hours
description	10.1371/journal.pone.0140446
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Cai Y. Leck H. Lim T.P. Teo J. Lee W. Hsu L.Y. Koh T.H. Tan T.T. Tan T.-Y. Kwa A.L.-H.
format	Article
author	Cai Y. Leck H. Lim T.P. Teo J. Lee W. Hsu L.Y. Koh T.H. Tan T.T. Tan T.-Y. Kwa A.L.-H.
author_sort	Cai Y.
title	Using an adenosine triphosphate bioluminescent assay to determine effective antibiotic combinations against carbapenem-resistant gram negative bacteria within 24 hours
title_short	Using an adenosine triphosphate bioluminescent assay to determine effective antibiotic combinations against carbapenem-resistant gram negative bacteria within 24 hours
title_full	Using an adenosine triphosphate bioluminescent assay to determine effective antibiotic combinations against carbapenem-resistant gram negative bacteria within 24 hours
title_fullStr	Using an adenosine triphosphate bioluminescent assay to determine effective antibiotic combinations against carbapenem-resistant gram negative bacteria within 24 hours
title_full_unstemmed	Using an adenosine triphosphate bioluminescent assay to determine effective antibiotic combinations against carbapenem-resistant gram negative bacteria within 24 hours
title_sort	using an adenosine triphosphate bioluminescent assay to determine effective antibiotic combinations against carbapenem-resistant gram negative bacteria within 24 hours
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161485
_version_	1781791771356823552

Using an adenosine triphosphate bioluminescent assay to determine effective antibiotic combinations against carbapenem-resistant gram negative bacteria within 24 hours

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