The overexpression of IQGAP1 and ?-catenin is associated with tumor progression in hepatocellular carcinoma in vitro and in vivo

• Main Authors: Jin X., Liu Y., Liu J., Lu W., Liang Z., Zhang D., Liu G., Zhu H., Xu N., Liang S.
• Other Authors: DEPT OF ELECTRICAL & COMPUTER ENGG
• Format: Article
• Published: 2019
• Subjects: beta catenin; IQ motif containing guanosine triphosphatase activating protein 1; small interfering RNA; guanosine triphosphatase activating protein; protein binding; adult; Article; cancer growth; carcinoma cell line; cell migration; cell proliferation; controlled study; histopathology; human; human cell; human tissue; in vitro study; in vivo study; liver cell carcinoma; major clinical study; metastasis; protein expression; protein function; protein protein interaction; regulatory mechanism; upregulation; biology; cell motion; cell nucleus; disease course; gene expression regulation; gene regulatory network; genetic transcription; genetics; liver tumor; metabolism; middle aged; pathology; protein transport; software; tumor cell line; beta Catenin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Computational Biology; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Liver Neoplasms; Middle Aged; Protein Binding; Protein Transport; ras GTPase-Activating Proteins; Software; Transcription, Genetic; Up-Regulation
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161492
• Institution: National University of Singapore

10.1371/journal.pone.0133770