Autocrine human growth hormone promotes invasive and cancer stem cell-like behavior of hepatocellular carcinoma cells by STAT3 dependent inhibition of CLAUDIN-1 expression

• المؤلفون الرئيسيون: Chen Y.-J., You M.-L., Chong Q.-Y., Pandey V., Zhuang Q.-S., Liu D.-X., Ma L., Zhu T., Lobie P.E.
• مؤلفون آخرون: PHARMACOLOGY
• التنسيق: مقال
• منشور في: 2020
• الموضوعات: beta actin; claudin 1; human growth hormone; STAT3 protein; STAT3 protein, human; apoptosis; Article; autocrine effect; cell function; cell invasion; cell migration; cell proliferation; cell survival; chromatin immunoprecipitation; colony formation; controlled study; gene mutation; genetic transfection; human; human cell; liver cell carcinoma; luciferase assay; MTT assay; protein expression; protein phosphorylation; reverse transcription polymerase chain reaction; signal transduction; transcription regulation; Western blotting; cancer stem cell; cell motion; down regulation; gene expression regulation; genetics; Hep-G2 cell line; liver tumor; metabolism; pathology; tumor cell line; tumor invasion; Apoptosis; Autocrine Communication; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Claudin-1; Down-Regulation; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Human Growth Hormone; Humans; Liver Neoplasms; Neoplasm Invasiveness; Neoplastic Stem Cells; STAT3 Transcription Factor
• الوصول للمادة أونلاين: https://scholarbank.nus.edu.sg/handle/10635/174614

10.3390/ijms18061274