Autocrine human growth hormone promotes invasive and cancer stem cell-like behavior of hepatocellular carcinoma cells by STAT3 dependent inhibition of CLAUDIN-1 expression

10.3390/ijms18061274

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Main Authors:	Chen Y.-J., You M.-L., Chong Q.-Y., Pandey V., Zhuang Q.-S., Liu D.-X., Ma L., Zhu T., Lobie P.E.
Other Authors:	PHARMACOLOGY
Format:	Article
Published:	2020
Subjects:	beta actin claudin 1 human growth hormone STAT3 protein STAT3 protein, human apoptosis Article autocrine effect cell function cell invasion cell migration cell proliferation cell survival chromatin immunoprecipitation colony formation controlled study gene mutation genetic transfection human human cell liver cell carcinoma luciferase assay MTT assay protein expression protein phosphorylation reverse transcription polymerase chain reaction signal transduction transcription regulation Western blotting cancer stem cell cell motion down regulation gene expression regulation genetics Hep-G2 cell line liver tumor metabolism pathology tumor cell line tumor invasion Apoptosis Autocrine Communication Carcinoma, Hepatocellular Cell Line, Tumor Cell Movement Cell Proliferation Claudin-1 Down-Regulation Gene Expression Regulation, Neoplastic Hep G2 Cells Human Growth Hormone Humans Liver Neoplasms Neoplasm Invasiveness Neoplastic Stem Cells STAT3 Transcription Factor
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174614
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1746142024-11-11T10:55:21Z Autocrine human growth hormone promotes invasive and cancer stem cell-like behavior of hepatocellular carcinoma cells by STAT3 dependent inhibition of CLAUDIN-1 expression Chen Y.-J. You M.-L. Chong Q.-Y. Pandey V. Zhuang Q.-S. Liu D.-X. Ma L. Zhu T. Lobie P.E. PHARMACOLOGY CANCER SCIENCE INSTITUTE OF SINGAPORE BIOCHEMISTRY beta actin claudin 1 human growth hormone STAT3 protein claudin 1 human growth hormone STAT3 protein STAT3 protein, human apoptosis Article autocrine effect cell function cell invasion cell migration cell proliferation cell survival chromatin immunoprecipitation colony formation controlled study gene mutation genetic transfection human human cell liver cell carcinoma luciferase assay MTT assay protein expression protein phosphorylation reverse transcription polymerase chain reaction signal transduction transcription regulation Western blotting autocrine effect cancer stem cell cell motion down regulation gene expression regulation genetics Hep-G2 cell line liver cell carcinoma liver tumor metabolism pathology tumor cell line tumor invasion Apoptosis Autocrine Communication Carcinoma, Hepatocellular Cell Line, Tumor Cell Movement Cell Proliferation Claudin-1 Down-Regulation Gene Expression Regulation, Neoplastic Hep G2 Cells Human Growth Hormone Humans Liver Neoplasms Neoplasm Invasiveness Neoplastic Stem Cells STAT3 Transcription Factor 10.3390/ijms18061274 International Journal of Molecular Sciences 18 6 1274 2020-09-08T03:25:52Z 2020-09-08T03:25:52Z 2017 Article Chen Y.-J., You M.-L., Chong Q.-Y., Pandey V., Zhuang Q.-S., Liu D.-X., Ma L., Zhu T., Lobie P.E. (2017). Autocrine human growth hormone promotes invasive and cancer stem cell-like behavior of hepatocellular carcinoma cells by STAT3 dependent inhibition of CLAUDIN-1 expression. International Journal of Molecular Sciences 18 (6) : 1274. ScholarBank@NUS Repository. https://doi.org/10.3390/ijms18061274 1661-6596 https://scholarbank.nus.edu.sg/handle/10635/174614 Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	beta actin claudin 1 human growth hormone STAT3 protein claudin 1 human growth hormone STAT3 protein STAT3 protein, human apoptosis Article autocrine effect cell function cell invasion cell migration cell proliferation cell survival chromatin immunoprecipitation colony formation controlled study gene mutation genetic transfection human human cell liver cell carcinoma luciferase assay MTT assay protein expression protein phosphorylation reverse transcription polymerase chain reaction signal transduction transcription regulation Western blotting autocrine effect cancer stem cell cell motion down regulation gene expression regulation genetics Hep-G2 cell line liver cell carcinoma liver tumor metabolism pathology tumor cell line tumor invasion Apoptosis Autocrine Communication Carcinoma, Hepatocellular Cell Line, Tumor Cell Movement Cell Proliferation Claudin-1 Down-Regulation Gene Expression Regulation, Neoplastic Hep G2 Cells Human Growth Hormone Humans Liver Neoplasms Neoplasm Invasiveness Neoplastic Stem Cells STAT3 Transcription Factor
spellingShingle	beta actin claudin 1 human growth hormone STAT3 protein claudin 1 human growth hormone STAT3 protein STAT3 protein, human apoptosis Article autocrine effect cell function cell invasion cell migration cell proliferation cell survival chromatin immunoprecipitation colony formation controlled study gene mutation genetic transfection human human cell liver cell carcinoma luciferase assay MTT assay protein expression protein phosphorylation reverse transcription polymerase chain reaction signal transduction transcription regulation Western blotting autocrine effect cancer stem cell cell motion down regulation gene expression regulation genetics Hep-G2 cell line liver cell carcinoma liver tumor metabolism pathology tumor cell line tumor invasion Apoptosis Autocrine Communication Carcinoma, Hepatocellular Cell Line, Tumor Cell Movement Cell Proliferation Claudin-1 Down-Regulation Gene Expression Regulation, Neoplastic Hep G2 Cells Human Growth Hormone Humans Liver Neoplasms Neoplasm Invasiveness Neoplastic Stem Cells STAT3 Transcription Factor Chen Y.-J. You M.-L. Chong Q.-Y. Pandey V. Zhuang Q.-S. Liu D.-X. Ma L. Zhu T. Lobie P.E. Autocrine human growth hormone promotes invasive and cancer stem cell-like behavior of hepatocellular carcinoma cells by STAT3 dependent inhibition of CLAUDIN-1 expression
description	10.3390/ijms18061274
author2	PHARMACOLOGY
author_facet	PHARMACOLOGY Chen Y.-J. You M.-L. Chong Q.-Y. Pandey V. Zhuang Q.-S. Liu D.-X. Ma L. Zhu T. Lobie P.E.
format	Article
author	Chen Y.-J. You M.-L. Chong Q.-Y. Pandey V. Zhuang Q.-S. Liu D.-X. Ma L. Zhu T. Lobie P.E.
author_sort	Chen Y.-J.
title	Autocrine human growth hormone promotes invasive and cancer stem cell-like behavior of hepatocellular carcinoma cells by STAT3 dependent inhibition of CLAUDIN-1 expression
title_short	Autocrine human growth hormone promotes invasive and cancer stem cell-like behavior of hepatocellular carcinoma cells by STAT3 dependent inhibition of CLAUDIN-1 expression
title_full	Autocrine human growth hormone promotes invasive and cancer stem cell-like behavior of hepatocellular carcinoma cells by STAT3 dependent inhibition of CLAUDIN-1 expression
title_fullStr	Autocrine human growth hormone promotes invasive and cancer stem cell-like behavior of hepatocellular carcinoma cells by STAT3 dependent inhibition of CLAUDIN-1 expression
title_full_unstemmed	Autocrine human growth hormone promotes invasive and cancer stem cell-like behavior of hepatocellular carcinoma cells by STAT3 dependent inhibition of CLAUDIN-1 expression
title_sort	autocrine human growth hormone promotes invasive and cancer stem cell-like behavior of hepatocellular carcinoma cells by stat3 dependent inhibition of claudin-1 expression
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/174614
_version_	1821201150380081152

Autocrine human growth hormone promotes invasive and cancer stem cell-like behavior of hepatocellular carcinoma cells by STAT3 dependent inhibition of CLAUDIN-1 expression

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