Low expression of DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2) correlates with poor prognosis in colorectal cancer

10.1371/journal.pone.0159954

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Main Authors:	Yan H., Hu K., Wu W., Li Y., Tian H., Chu Z., Koeffler H.P., Yin D.
Other Authors:	MEDICINE
Format:	Article
Published:	2019
Subjects:	dual specificity phosphatase dual specificity tyrosine phosphorylation regulated kinase 2 unclassified drug Dyrk kinase messenger RNA protein serine threonine kinase protein tyrosine kinase small interfering RNA tumor marker adult Article cancer prognosis cancer staging cancer survival cancer tissue cell invasion cell migration cell proliferation clinical feature colorectal cancer colorectal cancer cell line colorectal carcinoma controlled study down regulation DYRK2 gene female gene expression regulation HCT116 cell line human human cell human tissue immunohistochemistry in vitro study major clinical study male overall survival primary tumor protein expression real time polymerase chain reaction survival time SW480 cell line tumor localization biosynthesis cell cycle cell motion colorectal tumor disease free survival genetic database genetics HCT 116 cell line metabolism middle aged mortality RNA interference treatment outcome tumor cell line tumor invasion Biomarkers, Tumor Cell Cycle Cell Line, Tumor Cell Movement Cell Proliferation Colorectal Neoplasms Databases, Genetic Disease-Free Survival Female Gene Expression Regulation, Neoplastic HCT116 Cells Humans Male Middle Aged Neoplasm Invasiveness Protein-Serine-Threonine Kinases Protein-Tyrosine Kinases Real-Time Polymerase Chain Reaction RNA Interference RNA, Messenger RNA, Small Interfering Treatment Outcome
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161560
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1615602024-05-08T09:51:28Z Low expression of DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2) correlates with poor prognosis in colorectal cancer Yan H. Hu K. Wu W. Li Y. Tian H. Chu Z. Koeffler H.P. Yin D. MEDICINE dual specificity phosphatase dual specificity tyrosine phosphorylation regulated kinase 2 unclassified drug Dyrk kinase messenger RNA protein serine threonine kinase protein tyrosine kinase small interfering RNA tumor marker adult Article cancer prognosis cancer staging cancer survival cancer tissue cell invasion cell migration cell proliferation clinical feature colorectal cancer colorectal cancer cell line colorectal carcinoma controlled study down regulation DYRK2 gene female gene expression regulation HCT116 cell line human human cell human tissue immunohistochemistry in vitro study major clinical study male overall survival primary tumor protein expression real time polymerase chain reaction survival time SW480 cell line tumor localization biosynthesis cell cycle cell motion colorectal tumor disease free survival gene expression regulation genetic database genetics HCT 116 cell line metabolism middle aged mortality RNA interference treatment outcome tumor cell line tumor invasion Biomarkers, Tumor Cell Cycle Cell Line, Tumor Cell Movement Cell Proliferation Colorectal Neoplasms Databases, Genetic Disease-Free Survival Female Gene Expression Regulation, Neoplastic HCT116 Cells Humans Male Middle Aged Neoplasm Invasiveness Protein-Serine-Threonine Kinases Protein-Tyrosine Kinases Real-Time Polymerase Chain Reaction RNA Interference RNA, Messenger RNA, Small Interfering Treatment Outcome 10.1371/journal.pone.0159954 PLoS ONE 11 8 e0159954 2019-11-06T07:47:54Z 2019-11-06T07:47:54Z 2016 Article Yan H., Hu K., Wu W., Li Y., Tian H., Chu Z., Koeffler H.P., Yin D. (2016). Low expression of DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2) correlates with poor prognosis in colorectal cancer. PLoS ONE 11 (8) : e0159954. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0159954 19326203 https://scholarbank.nus.edu.sg/handle/10635/161560 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	dual specificity phosphatase dual specificity tyrosine phosphorylation regulated kinase 2 unclassified drug Dyrk kinase messenger RNA protein serine threonine kinase protein tyrosine kinase small interfering RNA tumor marker adult Article cancer prognosis cancer staging cancer survival cancer tissue cell invasion cell migration cell proliferation clinical feature colorectal cancer colorectal cancer cell line colorectal carcinoma controlled study down regulation DYRK2 gene female gene expression regulation HCT116 cell line human human cell human tissue immunohistochemistry in vitro study major clinical study male overall survival primary tumor protein expression real time polymerase chain reaction survival time SW480 cell line tumor localization biosynthesis cell cycle cell motion colorectal tumor disease free survival gene expression regulation genetic database genetics HCT 116 cell line metabolism middle aged mortality RNA interference treatment outcome tumor cell line tumor invasion Biomarkers, Tumor Cell Cycle Cell Line, Tumor Cell Movement Cell Proliferation Colorectal Neoplasms Databases, Genetic Disease-Free Survival Female Gene Expression Regulation, Neoplastic HCT116 Cells Humans Male Middle Aged Neoplasm Invasiveness Protein-Serine-Threonine Kinases Protein-Tyrosine Kinases Real-Time Polymerase Chain Reaction RNA Interference RNA, Messenger RNA, Small Interfering Treatment Outcome
spellingShingle	dual specificity phosphatase dual specificity tyrosine phosphorylation regulated kinase 2 unclassified drug Dyrk kinase messenger RNA protein serine threonine kinase protein tyrosine kinase small interfering RNA tumor marker adult Article cancer prognosis cancer staging cancer survival cancer tissue cell invasion cell migration cell proliferation clinical feature colorectal cancer colorectal cancer cell line colorectal carcinoma controlled study down regulation DYRK2 gene female gene expression regulation HCT116 cell line human human cell human tissue immunohistochemistry in vitro study major clinical study male overall survival primary tumor protein expression real time polymerase chain reaction survival time SW480 cell line tumor localization biosynthesis cell cycle cell motion colorectal tumor disease free survival gene expression regulation genetic database genetics HCT 116 cell line metabolism middle aged mortality RNA interference treatment outcome tumor cell line tumor invasion Biomarkers, Tumor Cell Cycle Cell Line, Tumor Cell Movement Cell Proliferation Colorectal Neoplasms Databases, Genetic Disease-Free Survival Female Gene Expression Regulation, Neoplastic HCT116 Cells Humans Male Middle Aged Neoplasm Invasiveness Protein-Serine-Threonine Kinases Protein-Tyrosine Kinases Real-Time Polymerase Chain Reaction RNA Interference RNA, Messenger RNA, Small Interfering Treatment Outcome Yan H. Hu K. Wu W. Li Y. Tian H. Chu Z. Koeffler H.P. Yin D. Low expression of DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2) correlates with poor prognosis in colorectal cancer
description	10.1371/journal.pone.0159954
author2	MEDICINE
author_facet	MEDICINE Yan H. Hu K. Wu W. Li Y. Tian H. Chu Z. Koeffler H.P. Yin D.
format	Article
author	Yan H. Hu K. Wu W. Li Y. Tian H. Chu Z. Koeffler H.P. Yin D.
author_sort	Yan H.
title	Low expression of DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2) correlates with poor prognosis in colorectal cancer
title_short	Low expression of DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2) correlates with poor prognosis in colorectal cancer
title_full	Low expression of DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2) correlates with poor prognosis in colorectal cancer
title_fullStr	Low expression of DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2) correlates with poor prognosis in colorectal cancer
title_full_unstemmed	Low expression of DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2) correlates with poor prognosis in colorectal cancer
title_sort	low expression of dyrk2 (dual specificity tyrosine phosphorylation regulated kinase 2) correlates with poor prognosis in colorectal cancer
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161560
_version_	1800913799916552192

Low expression of DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2) correlates with poor prognosis in colorectal cancer

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