Global DNA Hypermethylation in Down Syndrome Placenta

10.1371/journal.pgen.1003515

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Main Authors:	Jin S., Lee Y.K., Lim Y.C., Zheng Z., Lin X.M., Ng D.P.Y., Holbrook J.D., Law H.Y., Kwek K.Y.C., Yeo G.S.H., Ding C.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2019
Subjects:	adult article chorion villus chromosome 21 clinical article controlled study DNA methylation down regulation Down syndrome epigenetics female fetus gene gene location human human cell human tissue male multigene family NRSF gene phenotype placenta promoter region REST gene tet gene transcription regulation upregulation Chromosomes, Human, Pair 21 CpG Islands DNA Methylation DNA-Binding Proteins Down Syndrome Epigenesis, Genetic Female Gene Expression Regulation Humans Male Placenta Pregnancy Promoter Regions, Genetic Proto-Oncogene Proteins Repressor Proteins Sequence Analysis, DNA
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161621
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1616212023-10-31T08:28:31Z Global DNA Hypermethylation in Down Syndrome Placenta Jin S. Lee Y.K. Lim Y.C. Zheng Z. Lin X.M. Ng D.P.Y. Holbrook J.D. Law H.Y. Kwek K.Y.C. Yeo G.S.H. Ding C. DUKE-NUS MEDICAL SCHOOL adult article chorion villus chromosome 21 clinical article controlled study DNA methylation down regulation Down syndrome epigenetics female fetus gene gene location human human cell human tissue male multigene family NRSF gene phenotype placenta promoter region REST gene tet gene transcription regulation upregulation Chromosomes, Human, Pair 21 CpG Islands DNA Methylation DNA-Binding Proteins Down Syndrome Epigenesis, Genetic Female Gene Expression Regulation Humans Male Placenta Pregnancy Promoter Regions, Genetic Proto-Oncogene Proteins Repressor Proteins Sequence Analysis, DNA 10.1371/journal.pgen.1003515 PLoS Genetics 9 6 e1003515 2019-11-06T09:26:27Z 2019-11-06T09:26:27Z 2013 Article Jin S., Lee Y.K., Lim Y.C., Zheng Z., Lin X.M., Ng D.P.Y., Holbrook J.D., Law H.Y., Kwek K.Y.C., Yeo G.S.H., Ding C. (2013). Global DNA Hypermethylation in Down Syndrome Placenta. PLoS Genetics 9 (6) : e1003515. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pgen.1003515 15537390 https://scholarbank.nus.edu.sg/handle/10635/161621 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	adult article chorion villus chromosome 21 clinical article controlled study DNA methylation down regulation Down syndrome epigenetics female fetus gene gene location human human cell human tissue male multigene family NRSF gene phenotype placenta promoter region REST gene tet gene transcription regulation upregulation Chromosomes, Human, Pair 21 CpG Islands DNA Methylation DNA-Binding Proteins Down Syndrome Epigenesis, Genetic Female Gene Expression Regulation Humans Male Placenta Pregnancy Promoter Regions, Genetic Proto-Oncogene Proteins Repressor Proteins Sequence Analysis, DNA
spellingShingle	adult article chorion villus chromosome 21 clinical article controlled study DNA methylation down regulation Down syndrome epigenetics female fetus gene gene location human human cell human tissue male multigene family NRSF gene phenotype placenta promoter region REST gene tet gene transcription regulation upregulation Chromosomes, Human, Pair 21 CpG Islands DNA Methylation DNA-Binding Proteins Down Syndrome Epigenesis, Genetic Female Gene Expression Regulation Humans Male Placenta Pregnancy Promoter Regions, Genetic Proto-Oncogene Proteins Repressor Proteins Sequence Analysis, DNA Jin S. Lee Y.K. Lim Y.C. Zheng Z. Lin X.M. Ng D.P.Y. Holbrook J.D. Law H.Y. Kwek K.Y.C. Yeo G.S.H. Ding C. Global DNA Hypermethylation in Down Syndrome Placenta
description	10.1371/journal.pgen.1003515
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Jin S. Lee Y.K. Lim Y.C. Zheng Z. Lin X.M. Ng D.P.Y. Holbrook J.D. Law H.Y. Kwek K.Y.C. Yeo G.S.H. Ding C.
format	Article
author	Jin S. Lee Y.K. Lim Y.C. Zheng Z. Lin X.M. Ng D.P.Y. Holbrook J.D. Law H.Y. Kwek K.Y.C. Yeo G.S.H. Ding C.
author_sort	Jin S.
title	Global DNA Hypermethylation in Down Syndrome Placenta
title_short	Global DNA Hypermethylation in Down Syndrome Placenta
title_full	Global DNA Hypermethylation in Down Syndrome Placenta
title_fullStr	Global DNA Hypermethylation in Down Syndrome Placenta
title_full_unstemmed	Global DNA Hypermethylation in Down Syndrome Placenta
title_sort	global dna hypermethylation in down syndrome placenta
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161621
_version_	1781791804855681024

Global DNA Hypermethylation in Down Syndrome Placenta

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