A comprehensive model of the spatio-temporal stem cell and tissue organisation in the intestinal crypt

• Main Authors: Buske P., Galle J., Barker N., Aust G., Clevers H., Loeffler M.
• Other Authors: BIOCHEMISTRY
• Format: Article
• Published: 2019
• Subjects: beta catenin; Notch receptor; Wnt protein; analytic method; apoptosis; article; calculation; cell damage; cell interaction; cell lineage; cell migration; cell proliferation; cell subpopulation; controlled study; gene activity; gene expression; gene function; gene targeting; intestine crypt; mouse; nonhuman; prediction; simulation; stem cell; biological model; cytology; intestine; metabolism; signal transduction; Murinae; Apoptosis; Cell Proliferation; Intestines; Models, Biological; Receptors, Notch; Signal Transduction; Stem Cells; Wnt Proteins
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161656
• Institution: National University of Singapore

10.1371/journal.pcbi.1001045