Germline variation controls the architecture of somatic alterations in tumors

• Main Authors: Dworkin A.M., Ridd K., Bautista D., Allain D.C., Iwenofu O.H., Roy R., Bastian B.C., Toland A.E.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2019
• Subjects: allele; article; cancer risk; cancer susceptibility; chromosome 8q; chromosome aberration; comparative genomic hybridization; controlled study; cytoarchitecture; gene control; gene dosage; gene identification; gene locus; genetic predisposition; genetic variability; germ line; graft recipient; human; human tissue; microsatellite marker; mutational analysis; skin carcinoma; somatic mutation; squamous cell carcinoma; Allelic Imbalance; Chromosomes, Human, Pair 8; Comparative Genomic Hybridization; Genetic Loci; Germ-Line Mutation; Humans; Skin Neoplasms
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161658
• Institution: National University of Singapore

10.1371/journal.pgen.1001136