Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers

10.1038/s41467-018-03828-2

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Bibliographic Details
Main Authors:	Guo, Y.A, Chang, M.M, Huang, W, Ooi, W.F, Xing, M, Tan, P, Skanderup, A.J
Other Authors:	PHYSIOLOGY
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	transcription factor CTCF CTCF protein, human cancer chromosome gastroenteritis gene genomics mutation tumor Article binding site carcinogenesis chromosomal instability colorectal tumor controlled study digestive system cancer gene expression gene mutation human human cell human tissue indel mutation mutation rate single nucleotide polymorphism stomach tumor chromosome aberration conserved sequence dna mutational analysis false positive result gastrointestinal tumor gene expression profiling genetic database genetic epigenesis genetics human genome statistical model tumor cell line Binding Sites CCCTC-Binding Factor Cell Line, Tumor Chromosomal Instability Chromosome Aberrations Conserved Sequence Databases, Genetic DNA Mutational Analysis Epigenesis, Genetic False Positive Reactions Gastrointestinal Neoplasms Gene Expression Profiling Genome, Human Genomics Humans INDEL Mutation Models, Statistical Mutation Mutation Rate
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174228
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Institution:	National University of Singapore

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