Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers

10.1038/s41467-018-03828-2

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Main Authors:	Guo, Y.A, Chang, M.M, Huang, W, Ooi, W.F, Xing, M, Tan, P, Skanderup, A.J
Other Authors:	PHYSIOLOGY
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	transcription factor CTCF CTCF protein, human cancer chromosome gastroenteritis gene genomics mutation tumor Article binding site carcinogenesis chromosomal instability colorectal tumor controlled study digestive system cancer gene expression gene mutation human human cell human tissue indel mutation mutation rate single nucleotide polymorphism stomach tumor chromosome aberration conserved sequence dna mutational analysis false positive result gastrointestinal tumor gene expression profiling genetic database genetic epigenesis genetics human genome statistical model tumor cell line Binding Sites CCCTC-Binding Factor Cell Line, Tumor Chromosomal Instability Chromosome Aberrations Conserved Sequence Databases, Genetic DNA Mutational Analysis Epigenesis, Genetic False Positive Reactions Gastrointestinal Neoplasms Gene Expression Profiling Genome, Human Genomics Humans INDEL Mutation Models, Statistical Mutation Mutation Rate
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174228
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1742282024-04-25T08:06:54Z Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers Guo, Y.A Chang, M.M Huang, W Ooi, W.F Xing, M Tan, P Skanderup, A.J PHYSIOLOGY DEPARTMENT OF COMPUTER SCIENCE transcription factor CTCF CTCF protein, human transcription factor CTCF cancer chromosome gastroenteritis gene genomics mutation tumor Article binding site carcinogenesis chromosomal instability colorectal tumor controlled study digestive system cancer gene expression gene mutation human human cell human tissue indel mutation mutation rate single nucleotide polymorphism stomach tumor binding site chromosomal instability chromosome aberration conserved sequence dna mutational analysis false positive result gastrointestinal tumor gene expression profiling genetic database genetic epigenesis genetics genomics human genome indel mutation mutation statistical model tumor cell line Binding Sites CCCTC-Binding Factor Cell Line, Tumor Chromosomal Instability Chromosome Aberrations Conserved Sequence Databases, Genetic DNA Mutational Analysis Epigenesis, Genetic False Positive Reactions Gastrointestinal Neoplasms Gene Expression Profiling Genome, Human Genomics Humans INDEL Mutation Models, Statistical Mutation Mutation Rate 10.1038/s41467-018-03828-2 Nature Communications 9 1 1520 2020-09-04T01:50:25Z 2020-09-04T01:50:25Z 2018 Article Guo, Y.A, Chang, M.M, Huang, W, Ooi, W.F, Xing, M, Tan, P, Skanderup, A.J (2018). Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers. Nature Communications 9 (1) : 1520. ScholarBank@NUS Repository. https://doi.org/10.1038/s41467-018-03828-2 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/174228 Nature Publishing Group Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	transcription factor CTCF CTCF protein, human transcription factor CTCF cancer chromosome gastroenteritis gene genomics mutation tumor Article binding site carcinogenesis chromosomal instability colorectal tumor controlled study digestive system cancer gene expression gene mutation human human cell human tissue indel mutation mutation rate single nucleotide polymorphism stomach tumor binding site chromosomal instability chromosome aberration conserved sequence dna mutational analysis false positive result gastrointestinal tumor gene expression profiling genetic database genetic epigenesis genetics genomics human genome indel mutation mutation statistical model tumor cell line Binding Sites CCCTC-Binding Factor Cell Line, Tumor Chromosomal Instability Chromosome Aberrations Conserved Sequence Databases, Genetic DNA Mutational Analysis Epigenesis, Genetic False Positive Reactions Gastrointestinal Neoplasms Gene Expression Profiling Genome, Human Genomics Humans INDEL Mutation Models, Statistical Mutation Mutation Rate
spellingShingle	transcription factor CTCF CTCF protein, human transcription factor CTCF cancer chromosome gastroenteritis gene genomics mutation tumor Article binding site carcinogenesis chromosomal instability colorectal tumor controlled study digestive system cancer gene expression gene mutation human human cell human tissue indel mutation mutation rate single nucleotide polymorphism stomach tumor binding site chromosomal instability chromosome aberration conserved sequence dna mutational analysis false positive result gastrointestinal tumor gene expression profiling genetic database genetic epigenesis genetics genomics human genome indel mutation mutation statistical model tumor cell line Binding Sites CCCTC-Binding Factor Cell Line, Tumor Chromosomal Instability Chromosome Aberrations Conserved Sequence Databases, Genetic DNA Mutational Analysis Epigenesis, Genetic False Positive Reactions Gastrointestinal Neoplasms Gene Expression Profiling Genome, Human Genomics Humans INDEL Mutation Models, Statistical Mutation Mutation Rate Guo, Y.A Chang, M.M Huang, W Ooi, W.F Xing, M Tan, P Skanderup, A.J Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers
description	10.1038/s41467-018-03828-2
author2	PHYSIOLOGY
author_facet	PHYSIOLOGY Guo, Y.A Chang, M.M Huang, W Ooi, W.F Xing, M Tan, P Skanderup, A.J
format	Article
author	Guo, Y.A Chang, M.M Huang, W Ooi, W.F Xing, M Tan, P Skanderup, A.J
author_sort	Guo, Y.A
title	Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers
title_short	Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers
title_full	Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers
title_fullStr	Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers
title_full_unstemmed	Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers
title_sort	mutation hotspots at ctcf binding sites coupled to chromosomal instability in gastrointestinal cancers
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/174228
_version_	1800914224834150400

Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers

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