Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis

10.1371/journal.pgen.1000806

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Main Authors:	Guo Y., Tan L.-J., Lei S.-F., Yang T.-L., Chen X.-D., Zhang F., Chen Y., Pan F., Yan H., Liu X., Tian Q., Zhang Z.-X., Zhou Q., Qiu C., Dong S.-S., Xu X.-H., Guo Y.-F., Zhu X.-Z., Liu S.-L., Wang X.-L., Li X., Luo Y., Zhang L.-S., Li M., Wang J.-T., Wen T., Drees B., Hamilton J., Papasian C.J., Recker R.R., Song X.-P., Cheng J., Deng H.-W.
Other Authors:	DEPT OF CHEMISTRY
Format:	Article
Published:	2019
Subjects:	acetaldehyde aldehyde dehydrogenase ALDH7A1 protein, human adult aged aging aldh7a1 gene article bone density case control study Caucasian cell proliferation Chinese chromosome 5 controlled study female follow up gene gene identification gene replication genetic susceptibility genome analysis groups by age human major clinical study male ossification osteoblast osteoporosis pathogenesis risk factor single nucleotide polymorphism Asian genetic association genetic predisposition genetics middle aged pathophysiology Aged Aldehyde Dehydrogenase Asian Continental Ancestry Group Bone Density Case-Control Studies European Continental Ancestry Group Female Genetic Predisposition to Disease Genome-Wide Association Study Humans Male Middle Aged Osteoporosis Polymorphism, Single Nucleotide
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161668
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1616682023-10-31T08:27:39Z Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis Guo Y. Tan L.-J. Lei S.-F. Yang T.-L. Chen X.-D. Zhang F. Chen Y. Pan F. Yan H. Liu X. Tian Q. Zhang Z.-X. Zhou Q. Qiu C. Dong S.-S. Xu X.-H. Guo Y.-F. Zhu X.-Z. Liu S.-L. Wang X.-L. Li X. Luo Y. Zhang L.-S. Li M. Wang J.-T. Wen T. Drees B. Hamilton J. Papasian C.J. Recker R.R. Song X.-P. Cheng J. Deng H.-W. DEPT OF CHEMISTRY acetaldehyde aldehyde dehydrogenase ALDH7A1 protein, human adult aged aging aldh7a1 gene article bone density case control study Caucasian cell proliferation Chinese chromosome 5 controlled study female follow up gene gene identification gene replication genetic susceptibility genome analysis groups by age human major clinical study male ossification osteoblast osteoporosis pathogenesis risk factor single nucleotide polymorphism Asian genetic association genetic predisposition genetics middle aged pathophysiology Aged Aldehyde Dehydrogenase Asian Continental Ancestry Group Bone Density Case-Control Studies European Continental Ancestry Group Female Genetic Predisposition to Disease Genome-Wide Association Study Humans Male Middle Aged Osteoporosis Polymorphism, Single Nucleotide 10.1371/journal.pgen.1000806 PLoS Genetics 6 1 e1000806 2019-11-06T09:34:42Z 2019-11-06T09:34:42Z 2010 Article Guo Y., Tan L.-J., Lei S.-F., Yang T.-L., Chen X.-D., Zhang F., Chen Y., Pan F., Yan H., Liu X., Tian Q., Zhang Z.-X., Zhou Q., Qiu C., Dong S.-S., Xu X.-H., Guo Y.-F., Zhu X.-Z., Liu S.-L., Wang X.-L., Li X., Luo Y., Zhang L.-S., Li M., Wang J.-T., Wen T., Drees B., Hamilton J., Papasian C.J., Recker R.R., Song X.-P., Cheng J., Deng H.-W. (2010). Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis. PLoS Genetics 6 (1) : e1000806. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pgen.1000806 15537390 https://scholarbank.nus.edu.sg/handle/10635/161668 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	acetaldehyde aldehyde dehydrogenase ALDH7A1 protein, human adult aged aging aldh7a1 gene article bone density case control study Caucasian cell proliferation Chinese chromosome 5 controlled study female follow up gene gene identification gene replication genetic susceptibility genome analysis groups by age human major clinical study male ossification osteoblast osteoporosis pathogenesis risk factor single nucleotide polymorphism Asian genetic association genetic predisposition genetics middle aged pathophysiology Aged Aldehyde Dehydrogenase Asian Continental Ancestry Group Bone Density Case-Control Studies European Continental Ancestry Group Female Genetic Predisposition to Disease Genome-Wide Association Study Humans Male Middle Aged Osteoporosis Polymorphism, Single Nucleotide
spellingShingle	acetaldehyde aldehyde dehydrogenase ALDH7A1 protein, human adult aged aging aldh7a1 gene article bone density case control study Caucasian cell proliferation Chinese chromosome 5 controlled study female follow up gene gene identification gene replication genetic susceptibility genome analysis groups by age human major clinical study male ossification osteoblast osteoporosis pathogenesis risk factor single nucleotide polymorphism Asian genetic association genetic predisposition genetics middle aged pathophysiology Aged Aldehyde Dehydrogenase Asian Continental Ancestry Group Bone Density Case-Control Studies European Continental Ancestry Group Female Genetic Predisposition to Disease Genome-Wide Association Study Humans Male Middle Aged Osteoporosis Polymorphism, Single Nucleotide Guo Y. Tan L.-J. Lei S.-F. Yang T.-L. Chen X.-D. Zhang F. Chen Y. Pan F. Yan H. Liu X. Tian Q. Zhang Z.-X. Zhou Q. Qiu C. Dong S.-S. Xu X.-H. Guo Y.-F. Zhu X.-Z. Liu S.-L. Wang X.-L. Li X. Luo Y. Zhang L.-S. Li M. Wang J.-T. Wen T. Drees B. Hamilton J. Papasian C.J. Recker R.R. Song X.-P. Cheng J. Deng H.-W. Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis
description	10.1371/journal.pgen.1000806
author2	DEPT OF CHEMISTRY
author_facet	DEPT OF CHEMISTRY Guo Y. Tan L.-J. Lei S.-F. Yang T.-L. Chen X.-D. Zhang F. Chen Y. Pan F. Yan H. Liu X. Tian Q. Zhang Z.-X. Zhou Q. Qiu C. Dong S.-S. Xu X.-H. Guo Y.-F. Zhu X.-Z. Liu S.-L. Wang X.-L. Li X. Luo Y. Zhang L.-S. Li M. Wang J.-T. Wen T. Drees B. Hamilton J. Papasian C.J. Recker R.R. Song X.-P. Cheng J. Deng H.-W.
format	Article
author	Guo Y. Tan L.-J. Lei S.-F. Yang T.-L. Chen X.-D. Zhang F. Chen Y. Pan F. Yan H. Liu X. Tian Q. Zhang Z.-X. Zhou Q. Qiu C. Dong S.-S. Xu X.-H. Guo Y.-F. Zhu X.-Z. Liu S.-L. Wang X.-L. Li X. Luo Y. Zhang L.-S. Li M. Wang J.-T. Wen T. Drees B. Hamilton J. Papasian C.J. Recker R.R. Song X.-P. Cheng J. Deng H.-W.
author_sort	Guo Y.
title	Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis
title_short	Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis
title_full	Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis
title_fullStr	Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis
title_full_unstemmed	Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis
title_sort	genome-wide association study identifies aldh7a1 as a novel susceptibility gene for osteoporosis
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161668
_version_	1781791816998191104

Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis

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