MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis

10.1371/journal.ppat.1000474

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Main Authors:	Bowdish D.M.E., Sakamoto K., Kim M.-J., Kroos M., Mukhopadhyay S., Leifer C.A., Tryggvason K., Gordon S., Russell D.G.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2019
Subjects:	CD14 antigen cord factor immunoglobulin enhancer binding protein interleukin 1beta interleukin 6 marco receptor mitogen activated protein kinase mitogen activated protein kinase 1 mitogen activated protein kinase 3 myeloid differentiation factor 88 protein MD 2 scavenger receptor A toll like receptor 2 toll like receptor 4 tumor necrosis factor alpha unclassified drug cytokine immunoglobulin receptor MARCO protein, human Marco protein, mouse microsphere TLR2 protein, human TLR4 protein, human animal cell animal experiment article controlled study cytokine production enzyme activation enzyme phosphorylation human human cell mouse Mycobacterium tuberculosis nonhuman peritoneum macrophage phagosome protein expression protein localization receptor binding signal transduction animal C57BL mouse CHO cell Cricetulus cytoplasm fluorescence microscopy genetics hamster immunology macrophage metabolism Mus Animals Antigens, CD14 CHO Cells Cord Factors Cricetinae Cytokines Cytoplasm Humans Macrophages Mice Mice, Inbred C57BL Microscopy, Fluorescence Microspheres Phagosomes Receptors, Immunologic Scavenger Receptors, Class A Signal Transduction Toll-Like Receptor 2 Toll-Like Receptor 4
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161674
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1616742024-11-10T02:49:59Z MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis Bowdish D.M.E. Sakamoto K. Kim M.-J. Kroos M. Mukhopadhyay S. Leifer C.A. Tryggvason K. Gordon S. Russell D.G. DUKE-NUS MEDICAL SCHOOL CD14 antigen cord factor immunoglobulin enhancer binding protein interleukin 1beta interleukin 6 marco receptor mitogen activated protein kinase mitogen activated protein kinase 1 mitogen activated protein kinase 3 myeloid differentiation factor 88 protein MD 2 scavenger receptor A toll like receptor 2 toll like receptor 4 tumor necrosis factor alpha unclassified drug CD14 antigen cytokine immunoglobulin receptor MARCO protein, human Marco protein, mouse microsphere scavenger receptor A TLR2 protein, human TLR4 protein, human toll like receptor 2 animal cell animal experiment article controlled study cytokine production enzyme activation enzyme phosphorylation human human cell mouse Mycobacterium tuberculosis nonhuman peritoneum macrophage phagosome protein expression protein localization receptor binding signal transduction animal C57BL mouse CHO cell Cricetulus cytoplasm fluorescence microscopy genetics hamster immunology macrophage metabolism Mycobacterium tuberculosis Mus Mycobacterium tuberculosis Animals Antigens, CD14 CHO Cells Cord Factors Cricetinae Cricetulus Cytokines Cytoplasm Humans Macrophages Mice Mice, Inbred C57BL Microscopy, Fluorescence Microspheres Mycobacterium tuberculosis Phagosomes Receptors, Immunologic Scavenger Receptors, Class A Signal Transduction Toll-Like Receptor 2 Toll-Like Receptor 4 10.1371/journal.ppat.1000474 PLoS Pathogens 5 6 e1000474 2019-11-06T09:35:48Z 2019-11-06T09:35:48Z 2009 Article Bowdish D.M.E., Sakamoto K., Kim M.-J., Kroos M., Mukhopadhyay S., Leifer C.A., Tryggvason K., Gordon S., Russell D.G. (2009). MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis. PLoS Pathogens 5 (6) : e1000474. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.ppat.1000474 15537366 https://scholarbank.nus.edu.sg/handle/10635/161674 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	CD14 antigen cord factor immunoglobulin enhancer binding protein interleukin 1beta interleukin 6 marco receptor mitogen activated protein kinase mitogen activated protein kinase 1 mitogen activated protein kinase 3 myeloid differentiation factor 88 protein MD 2 scavenger receptor A toll like receptor 2 toll like receptor 4 tumor necrosis factor alpha unclassified drug CD14 antigen cytokine immunoglobulin receptor MARCO protein, human Marco protein, mouse microsphere scavenger receptor A TLR2 protein, human TLR4 protein, human toll like receptor 2 animal cell animal experiment article controlled study cytokine production enzyme activation enzyme phosphorylation human human cell mouse Mycobacterium tuberculosis nonhuman peritoneum macrophage phagosome protein expression protein localization receptor binding signal transduction animal C57BL mouse CHO cell Cricetulus cytoplasm fluorescence microscopy genetics hamster immunology macrophage metabolism Mycobacterium tuberculosis Mus Mycobacterium tuberculosis Animals Antigens, CD14 CHO Cells Cord Factors Cricetinae Cricetulus Cytokines Cytoplasm Humans Macrophages Mice Mice, Inbred C57BL Microscopy, Fluorescence Microspheres Mycobacterium tuberculosis Phagosomes Receptors, Immunologic Scavenger Receptors, Class A Signal Transduction Toll-Like Receptor 2 Toll-Like Receptor 4
spellingShingle	CD14 antigen cord factor immunoglobulin enhancer binding protein interleukin 1beta interleukin 6 marco receptor mitogen activated protein kinase mitogen activated protein kinase 1 mitogen activated protein kinase 3 myeloid differentiation factor 88 protein MD 2 scavenger receptor A toll like receptor 2 toll like receptor 4 tumor necrosis factor alpha unclassified drug CD14 antigen cytokine immunoglobulin receptor MARCO protein, human Marco protein, mouse microsphere scavenger receptor A TLR2 protein, human TLR4 protein, human toll like receptor 2 animal cell animal experiment article controlled study cytokine production enzyme activation enzyme phosphorylation human human cell mouse Mycobacterium tuberculosis nonhuman peritoneum macrophage phagosome protein expression protein localization receptor binding signal transduction animal C57BL mouse CHO cell Cricetulus cytoplasm fluorescence microscopy genetics hamster immunology macrophage metabolism Mycobacterium tuberculosis Mus Mycobacterium tuberculosis Animals Antigens, CD14 CHO Cells Cord Factors Cricetinae Cricetulus Cytokines Cytoplasm Humans Macrophages Mice Mice, Inbred C57BL Microscopy, Fluorescence Microspheres Mycobacterium tuberculosis Phagosomes Receptors, Immunologic Scavenger Receptors, Class A Signal Transduction Toll-Like Receptor 2 Toll-Like Receptor 4 Bowdish D.M.E. Sakamoto K. Kim M.-J. Kroos M. Mukhopadhyay S. Leifer C.A. Tryggvason K. Gordon S. Russell D.G. MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis
description	10.1371/journal.ppat.1000474
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Bowdish D.M.E. Sakamoto K. Kim M.-J. Kroos M. Mukhopadhyay S. Leifer C.A. Tryggvason K. Gordon S. Russell D.G.
format	Article
author	Bowdish D.M.E. Sakamoto K. Kim M.-J. Kroos M. Mukhopadhyay S. Leifer C.A. Tryggvason K. Gordon S. Russell D.G.
author_sort	Bowdish D.M.E.
title	MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis
title_short	MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis
title_full	MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis
title_fullStr	MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis
title_full_unstemmed	MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis
title_sort	marco, tlr2, and cd14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and mycobacterium tuberculosis
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161674
_version_	1821203977198370816

MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis

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