Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

• Main Authors: Ku M., Koche R.P., Rheinbay E., Mendenhall E.M., Endoh M., Mikkelsen T.S., Presser A., Nusbaum C., Xie X., Chi A.S., Adli M., Kasif S., Ptaszek L.M., Cowan C.A., Lander E.S., Koseki H., Bernstein B.E.
• Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
• Format: Article
• Published: 2019
• Subjects: cell cycle protein; histone; lysine; protein PRC1; protein PRC2; unclassified drug; Jmjd3 protein, mouse; n demethylase; polycomb group protein; repressor protein; animal cell; article; chromatin immunoprecipitation; controlled study; CpG island; embryonic stem cell; female; human; human cell; male; methylation; mouse; nonhuman; protein analysis; protein binding; protein domain; protein function; protein localization; protein modification; protein motif; protein structure; regulator gene; animal; biology; chemistry; chromatin; chromosome map; genetic epigenesis; genetics; genome; human genome; metabolism; pluripotent stem cell; promoter region; protein tertiary structure; Animals; Chromatin; Chromatin Immunoprecipitation; Chromosome Mapping; Computational Biology; CpG Islands; Embryonic Stem Cells; Epigenesis, Genetic; Genome; Genome, Human; Histones; Humans; Methylation; Mice; Oxidoreductases, N-Demethylating; Pluripotent Stem Cells; Promoter Regions, Genetic; Protein Structure, Tertiary; Repressor Proteins
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161683
• Institution: National University of Singapore

10.1371/journal.pgen.1000242