Pro-Inflammatory Cytokines, IFNγ and TNFα, Influence Immune Properties of Human Bone Marrow and Wharton Jelly Mesenchymal Stem Cells Differentially

• Main Authors: Prasanna S.J., Gopalakrishnan D., Shankar S.R., Vasandan A.B.
• Other Authors: PHYSIOLOGY
• Format: Article
• Published: 2019
• Subjects: alloantigen; cytokine; cytotoxic T lymphocyte antigen 4; gamma interferon; indoleamine 2,3 dioxygenase; interleukin 2; methyltestosterone; prostaglandin E2; scatter factor; tumor necrosis factor alpha; cyclooxygenase 2; PTGS2 protein, human; article; bone marrow; cell differentiation; coculture; controlled study; cytokine release; enzyme activity; human; human cell; immunocytochemistry; immunomodulation; immunosuppressive treatment; in vitro study; kinetics; lymphocyte proliferation; mesenchymal stem cell; protein blood level; Wharton jelly derived stem cell; adipocyte; bone marrow cell; cartilage cell; cell culture; cytology; drug effect; female; flow cytometry; genetics; immunology; immunophenotyping; metabolism; mixed lymphocyte culture; osteoblast; reverse transcription polymerase chain reaction; stroma cell; umbilical cord; Adipocytes; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Chondrocytes; Coculture Techniques; Cyclooxygenase 2; Cytokines; Female; Flow Cytometry; Humans; Immunophenotyping; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Lymphocyte Culture Test, Mixed; Mesenchymal Stem Cells; Osteoblasts; Reverse Transcriptase Polymerase Chain Reaction; Stromal Cells; Tumor Necrosis Factor-alpha; Umbilical Cord
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161819
• Institution: National University of Singapore

10.1371/journal.pone.0009016