Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells

10.1371/journal.pone.0004268

Saved in:
Bibliographic Details
Main Authors: Guzman-Ayala M., Lee K.L., Mavrakis K.J., Goggolidou P., Norris D.P., Episkopou V.
Other Authors: DUKE-NUS MEDICAL SCHOOL
Format: Article
Published: 2019
Subjects:
Online Access:https://scholarbank.nus.edu.sg/handle/10635/161843
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: National University of Singapore
id sg-nus-scholar.10635-161843
record_format dspace
spelling sg-nus-scholar.10635-1618432023-08-02T21:31:17Z Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells Guzman-Ayala M. Lee K.L. Mavrakis K.J. Goggolidou P. Norris D.P. Episkopou V. DUKE-NUS MEDICAL SCHOOL 4 [4 (1,3 benzodioxol 5 yl) 5 (2 pyridinyl) 1h imidazol 2 yl]benzamide Smad2 protein Smad3 protein Smad7 protein 1,3 dioxolane derivative 4 (5 benzo(1,3)dioxol 5 yl 4 pyridin 2 yl 1H imidazol 2 yl)benzamide 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide activin receptor 1 Acvr1b protein, mouse Arkadia protein, mouse benzamide derivative Nodal protein, mouse protein Nodal Smad2 protein Smad2 protein, mouse Smad3 protein Smad3 protein, mouse transforming growth factor beta ubiquitin animal cell animal tissue article controlled study DNA microarray embryo embryo development embryonic stem cell feedback system gene activation gene expression profiling gene identification gene repression genetic transcription morphogenesis mouse nonhuman nucleotide sequence protein synthesis signal transduction transcription regulation unindexed sequence animal biological model flow cytometry gene expression regulation metabolism Vertebrata Activin Receptors, Type I Animals Benzamides Dioxoles Embryonic Stem Cells Flow Cytometry Gene Expression Regulation, Developmental Mice Models, Biological Nodal Protein Signal Transduction Smad2 Protein Smad3 Protein Transcription, Genetic Transforming Growth Factor beta Ubiquitin 10.1371/journal.pone.0004268 PLoS ONE 4 1 e4268 2019-11-08T00:54:12Z 2019-11-08T00:54:12Z 2009 Article Guzman-Ayala M., Lee K.L., Mavrakis K.J., Goggolidou P., Norris D.P., Episkopou V. (2009). Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells. PLoS ONE 4 (1) : e4268. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0004268 19326203 https://scholarbank.nus.edu.sg/handle/10635/161843 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic 4 [4 (1,3 benzodioxol 5 yl) 5 (2 pyridinyl) 1h imidazol 2 yl]benzamide
Smad2 protein
Smad3 protein
Smad7 protein
1,3 dioxolane derivative
4 (5 benzo(1,3)dioxol 5 yl 4 pyridin 2 yl 1H imidazol 2 yl)benzamide
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide
activin receptor 1
Acvr1b protein, mouse
Arkadia protein, mouse
benzamide derivative
Nodal protein, mouse
protein Nodal
Smad2 protein
Smad2 protein, mouse
Smad3 protein
Smad3 protein, mouse
transforming growth factor beta
ubiquitin
animal cell
animal tissue
article
controlled study
DNA microarray
embryo
embryo development
embryonic stem cell
feedback system
gene activation
gene expression profiling
gene identification
gene repression
genetic transcription
morphogenesis
mouse
nonhuman
nucleotide sequence
protein synthesis
signal transduction
transcription regulation
unindexed sequence
animal
biological model
flow cytometry
gene expression regulation
metabolism
Vertebrata
Activin Receptors, Type I
Animals
Benzamides
Dioxoles
Embryonic Stem Cells
Flow Cytometry
Gene Expression Regulation, Developmental
Mice
Models, Biological
Nodal Protein
Signal Transduction
Smad2 Protein
Smad3 Protein
Transcription, Genetic
Transforming Growth Factor beta
Ubiquitin
spellingShingle 4 [4 (1,3 benzodioxol 5 yl) 5 (2 pyridinyl) 1h imidazol 2 yl]benzamide
Smad2 protein
Smad3 protein
Smad7 protein
1,3 dioxolane derivative
4 (5 benzo(1,3)dioxol 5 yl 4 pyridin 2 yl 1H imidazol 2 yl)benzamide
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide
activin receptor 1
Acvr1b protein, mouse
Arkadia protein, mouse
benzamide derivative
Nodal protein, mouse
protein Nodal
Smad2 protein
Smad2 protein, mouse
Smad3 protein
Smad3 protein, mouse
transforming growth factor beta
ubiquitin
animal cell
animal tissue
article
controlled study
DNA microarray
embryo
embryo development
embryonic stem cell
feedback system
gene activation
gene expression profiling
gene identification
gene repression
genetic transcription
morphogenesis
mouse
nonhuman
nucleotide sequence
protein synthesis
signal transduction
transcription regulation
unindexed sequence
animal
biological model
flow cytometry
gene expression regulation
metabolism
Vertebrata
Activin Receptors, Type I
Animals
Benzamides
Dioxoles
Embryonic Stem Cells
Flow Cytometry
Gene Expression Regulation, Developmental
Mice
Models, Biological
Nodal Protein
Signal Transduction
Smad2 Protein
Smad3 Protein
Transcription, Genetic
Transforming Growth Factor beta
Ubiquitin
Guzman-Ayala M.
Lee K.L.
Mavrakis K.J.
Goggolidou P.
Norris D.P.
Episkopou V.
Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells
description 10.1371/journal.pone.0004268
author2 DUKE-NUS MEDICAL SCHOOL
author_facet DUKE-NUS MEDICAL SCHOOL
Guzman-Ayala M.
Lee K.L.
Mavrakis K.J.
Goggolidou P.
Norris D.P.
Episkopou V.
format Article
author Guzman-Ayala M.
Lee K.L.
Mavrakis K.J.
Goggolidou P.
Norris D.P.
Episkopou V.
author_sort Guzman-Ayala M.
title Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells
title_short Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells
title_full Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells
title_fullStr Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells
title_full_unstemmed Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells
title_sort graded smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells
publishDate 2019
url https://scholarbank.nus.edu.sg/handle/10635/161843
_version_ 1773550458440253440