Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells
10.1371/journal.pone.0004268
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sg-nus-scholar.10635-1618432023-08-02T21:31:17Z Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells Guzman-Ayala M. Lee K.L. Mavrakis K.J. Goggolidou P. Norris D.P. Episkopou V. DUKE-NUS MEDICAL SCHOOL 4 [4 (1,3 benzodioxol 5 yl) 5 (2 pyridinyl) 1h imidazol 2 yl]benzamide Smad2 protein Smad3 protein Smad7 protein 1,3 dioxolane derivative 4 (5 benzo(1,3)dioxol 5 yl 4 pyridin 2 yl 1H imidazol 2 yl)benzamide 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide activin receptor 1 Acvr1b protein, mouse Arkadia protein, mouse benzamide derivative Nodal protein, mouse protein Nodal Smad2 protein Smad2 protein, mouse Smad3 protein Smad3 protein, mouse transforming growth factor beta ubiquitin animal cell animal tissue article controlled study DNA microarray embryo embryo development embryonic stem cell feedback system gene activation gene expression profiling gene identification gene repression genetic transcription morphogenesis mouse nonhuman nucleotide sequence protein synthesis signal transduction transcription regulation unindexed sequence animal biological model flow cytometry gene expression regulation metabolism Vertebrata Activin Receptors, Type I Animals Benzamides Dioxoles Embryonic Stem Cells Flow Cytometry Gene Expression Regulation, Developmental Mice Models, Biological Nodal Protein Signal Transduction Smad2 Protein Smad3 Protein Transcription, Genetic Transforming Growth Factor beta Ubiquitin 10.1371/journal.pone.0004268 PLoS ONE 4 1 e4268 2019-11-08T00:54:12Z 2019-11-08T00:54:12Z 2009 Article Guzman-Ayala M., Lee K.L., Mavrakis K.J., Goggolidou P., Norris D.P., Episkopou V. (2009). Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells. PLoS ONE 4 (1) : e4268. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0004268 19326203 https://scholarbank.nus.edu.sg/handle/10635/161843 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101 |
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4 [4 (1,3 benzodioxol 5 yl) 5 (2 pyridinyl) 1h imidazol 2 yl]benzamide Smad2 protein Smad3 protein Smad7 protein 1,3 dioxolane derivative 4 (5 benzo(1,3)dioxol 5 yl 4 pyridin 2 yl 1H imidazol 2 yl)benzamide 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide activin receptor 1 Acvr1b protein, mouse Arkadia protein, mouse benzamide derivative Nodal protein, mouse protein Nodal Smad2 protein Smad2 protein, mouse Smad3 protein Smad3 protein, mouse transforming growth factor beta ubiquitin animal cell animal tissue article controlled study DNA microarray embryo embryo development embryonic stem cell feedback system gene activation gene expression profiling gene identification gene repression genetic transcription morphogenesis mouse nonhuman nucleotide sequence protein synthesis signal transduction transcription regulation unindexed sequence animal biological model flow cytometry gene expression regulation metabolism Vertebrata Activin Receptors, Type I Animals Benzamides Dioxoles Embryonic Stem Cells Flow Cytometry Gene Expression Regulation, Developmental Mice Models, Biological Nodal Protein Signal Transduction Smad2 Protein Smad3 Protein Transcription, Genetic Transforming Growth Factor beta Ubiquitin |
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4 [4 (1,3 benzodioxol 5 yl) 5 (2 pyridinyl) 1h imidazol 2 yl]benzamide Smad2 protein Smad3 protein Smad7 protein 1,3 dioxolane derivative 4 (5 benzo(1,3)dioxol 5 yl 4 pyridin 2 yl 1H imidazol 2 yl)benzamide 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide activin receptor 1 Acvr1b protein, mouse Arkadia protein, mouse benzamide derivative Nodal protein, mouse protein Nodal Smad2 protein Smad2 protein, mouse Smad3 protein Smad3 protein, mouse transforming growth factor beta ubiquitin animal cell animal tissue article controlled study DNA microarray embryo embryo development embryonic stem cell feedback system gene activation gene expression profiling gene identification gene repression genetic transcription morphogenesis mouse nonhuman nucleotide sequence protein synthesis signal transduction transcription regulation unindexed sequence animal biological model flow cytometry gene expression regulation metabolism Vertebrata Activin Receptors, Type I Animals Benzamides Dioxoles Embryonic Stem Cells Flow Cytometry Gene Expression Regulation, Developmental Mice Models, Biological Nodal Protein Signal Transduction Smad2 Protein Smad3 Protein Transcription, Genetic Transforming Growth Factor beta Ubiquitin Guzman-Ayala M. Lee K.L. Mavrakis K.J. Goggolidou P. Norris D.P. Episkopou V. Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells |
description |
10.1371/journal.pone.0004268 |
author2 |
DUKE-NUS MEDICAL SCHOOL |
author_facet |
DUKE-NUS MEDICAL SCHOOL Guzman-Ayala M. Lee K.L. Mavrakis K.J. Goggolidou P. Norris D.P. Episkopou V. |
format |
Article |
author |
Guzman-Ayala M. Lee K.L. Mavrakis K.J. Goggolidou P. Norris D.P. Episkopou V. |
author_sort |
Guzman-Ayala M. |
title |
Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells |
title_short |
Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells |
title_full |
Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells |
title_fullStr |
Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells |
title_full_unstemmed |
Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells |
title_sort |
graded smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells |
publishDate |
2019 |
url |
https://scholarbank.nus.edu.sg/handle/10635/161843 |
_version_ |
1773550458440253440 |