Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition

10.1371/journal.pone.0002823

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Main Authors:	Ong C.-T., Sedy J.R., Murphy K.M., Kopan R.
Other Authors:	BIOLOGY (NU)
Format:	Article
Published:	2019
Subjects:	CD4 antigen cytokine gamma secretase immunoglobulin J recombination signal sequence binding protein interleukin 12 interleukin 4 Jagged1 Notch receptor Notch1 receptor Notch2 receptor presenilin animal cell article CD4+ T lymphocyte cell expansion cell fate controlled study cytokine production cytokine release human human cell lymphocyte differentiation lymphocyte proliferation mouse nonhuman protein degradation protein expression protein function Th1 cell Th2 cell animal C57BL mouse cell differentiation cell lineage CHO cell Cricetulus hamster metabolism Animals Cell Differentiation Cell Lineage CHO Cells Cricetinae Cytokines Interleukin-12 Interleukin-4 Mice Mice, Inbred C57BL Presenilins Receptors, Notch Th1 Cells Th2 Cells
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161850
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1618502023-11-01T07:28:27Z Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition Ong C.-T. Sedy J.R. Murphy K.M. Kopan R. BIOLOGY (NU) CD4 antigen cytokine gamma secretase immunoglobulin J recombination signal sequence binding protein interleukin 12 interleukin 4 Jagged1 Notch receptor Notch1 receptor Notch2 receptor presenilin cytokine Notch receptor presenilin animal cell article CD4+ T lymphocyte cell expansion cell fate controlled study cytokine production cytokine release human human cell lymphocyte differentiation lymphocyte proliferation mouse nonhuman protein degradation protein expression protein function Th1 cell Th2 cell animal C57BL mouse cell differentiation cell lineage CHO cell Cricetulus hamster metabolism Animals Cell Differentiation Cell Lineage CHO Cells Cricetinae Cricetulus Cytokines Interleukin-12 Interleukin-4 Mice Mice, Inbred C57BL Presenilins Receptors, Notch Th1 Cells Th2 Cells 10.1371/journal.pone.0002823 PLoS ONE 3 7 e2823 2019-11-08T00:55:37Z 2019-11-08T00:55:37Z 2008 Article Ong C.-T., Sedy J.R., Murphy K.M., Kopan R. (2008). Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition. PLoS ONE 3 (7) : e2823. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0002823 19326203 https://scholarbank.nus.edu.sg/handle/10635/161850 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	CD4 antigen cytokine gamma secretase immunoglobulin J recombination signal sequence binding protein interleukin 12 interleukin 4 Jagged1 Notch receptor Notch1 receptor Notch2 receptor presenilin cytokine Notch receptor presenilin animal cell article CD4+ T lymphocyte cell expansion cell fate controlled study cytokine production cytokine release human human cell lymphocyte differentiation lymphocyte proliferation mouse nonhuman protein degradation protein expression protein function Th1 cell Th2 cell animal C57BL mouse cell differentiation cell lineage CHO cell Cricetulus hamster metabolism Animals Cell Differentiation Cell Lineage CHO Cells Cricetinae Cricetulus Cytokines Interleukin-12 Interleukin-4 Mice Mice, Inbred C57BL Presenilins Receptors, Notch Th1 Cells Th2 Cells
spellingShingle	CD4 antigen cytokine gamma secretase immunoglobulin J recombination signal sequence binding protein interleukin 12 interleukin 4 Jagged1 Notch receptor Notch1 receptor Notch2 receptor presenilin cytokine Notch receptor presenilin animal cell article CD4+ T lymphocyte cell expansion cell fate controlled study cytokine production cytokine release human human cell lymphocyte differentiation lymphocyte proliferation mouse nonhuman protein degradation protein expression protein function Th1 cell Th2 cell animal C57BL mouse cell differentiation cell lineage CHO cell Cricetulus hamster metabolism Animals Cell Differentiation Cell Lineage CHO Cells Cricetinae Cricetulus Cytokines Interleukin-12 Interleukin-4 Mice Mice, Inbred C57BL Presenilins Receptors, Notch Th1 Cells Th2 Cells Ong C.-T. Sedy J.R. Murphy K.M. Kopan R. Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition
description	10.1371/journal.pone.0002823
author2	BIOLOGY (NU)
author_facet	BIOLOGY (NU) Ong C.-T. Sedy J.R. Murphy K.M. Kopan R.
format	Article
author	Ong C.-T. Sedy J.R. Murphy K.M. Kopan R.
author_sort	Ong C.-T.
title	Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition
title_short	Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition
title_full	Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition
title_fullStr	Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition
title_full_unstemmed	Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition
title_sort	notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct th1/th2 fate acquisition
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161850
_version_	1781791848284553216

Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition

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