Saturated fatty acids modulate cell response to DNA damage: Implication for their role in tumorigenesis
10.1371/journal.pone.0002329
Saved in:
Main Authors: | , , , , , , , , , , |
---|---|
Other Authors: | |
Format: | Article |
Published: |
2019
|
Subjects: | |
Online Access: | https://scholarbank.nus.edu.sg/handle/10635/161854 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | National University of Singapore |
id |
sg-nus-scholar.10635-161854 |
---|---|
record_format |
dspace |
spelling |
sg-nus-scholar.10635-1618542024-11-10T21:25:24Z Saturated fatty acids modulate cell response to DNA damage: Implication for their role in tumorigenesis Zeng L. Wu G.-Z. Goh K.J. Lee Y.M. Ng C.C. You A.B. Wang J. Jia D. Hao A. Yu Q. Li B. PHYSIOLOGY BIOLOGICAL SCIENCES DUKE-NUS MEDICAL SCHOOL actin DNA double stranded DNA doxorubicin fatty acid synthase hydroxyurea myristic acid palmitic acid protein Bax protein p21 protein p53 saturated fatty acid single stranded DNA stearic acid fatty acid fatty acid synthase protein p21 protein p53 animal cell apoptosis article cancer cell carcinogenesis cell cycle arrest cell proliferation cell strain 3T3 cell strain HCT116 cell strain MCF 7 cell transformation controlled study DNA damage DNA strand breakage embryo enzyme inhibition fatty acid synthesis fibroblast gene expression regulation growth inhibition human human cell malignant neoplastic disease mouse nonhuman osteoblast protein expression signal transduction tumor growth animal biosynthesis cell line drug antagonism drug effect fluorescent antibody technique ionizing radiation metabolism phosphorylation physiology Western blotting Murinae Animals Blotting, Western Cell Line Cell Proliferation DNA Damage Doxorubicin Fatty Acid Synthetase Complex Fatty Acids Fluorescent Antibody Technique Humans Hydroxyurea Mice Oncogene Protein p21(ras) Osteoblasts Phosphorylation Radiation, Ionizing Tumor Suppressor Protein p53 10.1371/journal.pone.0002329 PLoS ONE 3 6 e2329 2019-11-08T00:56:28Z 2019-11-08T00:56:28Z 2008 Article Zeng L., Wu G.-Z., Goh K.J., Lee Y.M., Ng C.C., You A.B., Wang J., Jia D., Hao A., Yu Q., Li B. (2008). Saturated fatty acids modulate cell response to DNA damage: Implication for their role in tumorigenesis. PLoS ONE 3 (6) : e2329. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0002329 19326203 https://scholarbank.nus.edu.sg/handle/10635/161854 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101 |
institution |
National University of Singapore |
building |
NUS Library |
continent |
Asia |
country |
Singapore Singapore |
content_provider |
NUS Library |
collection |
ScholarBank@NUS |
topic |
actin DNA double stranded DNA doxorubicin fatty acid synthase hydroxyurea myristic acid palmitic acid protein Bax protein p21 protein p53 saturated fatty acid single stranded DNA stearic acid fatty acid fatty acid synthase protein p21 protein p53 animal cell apoptosis article cancer cell carcinogenesis cell cycle arrest cell proliferation cell strain 3T3 cell strain HCT116 cell strain MCF 7 cell transformation controlled study DNA damage DNA strand breakage embryo enzyme inhibition fatty acid synthesis fibroblast gene expression regulation growth inhibition human human cell malignant neoplastic disease mouse nonhuman osteoblast protein expression signal transduction tumor growth animal biosynthesis cell line drug antagonism drug effect fluorescent antibody technique ionizing radiation metabolism phosphorylation physiology Western blotting Murinae Animals Blotting, Western Cell Line Cell Proliferation DNA Damage Doxorubicin Fatty Acid Synthetase Complex Fatty Acids Fluorescent Antibody Technique Humans Hydroxyurea Mice Oncogene Protein p21(ras) Osteoblasts Phosphorylation Radiation, Ionizing Tumor Suppressor Protein p53 |
spellingShingle |
actin DNA double stranded DNA doxorubicin fatty acid synthase hydroxyurea myristic acid palmitic acid protein Bax protein p21 protein p53 saturated fatty acid single stranded DNA stearic acid fatty acid fatty acid synthase protein p21 protein p53 animal cell apoptosis article cancer cell carcinogenesis cell cycle arrest cell proliferation cell strain 3T3 cell strain HCT116 cell strain MCF 7 cell transformation controlled study DNA damage DNA strand breakage embryo enzyme inhibition fatty acid synthesis fibroblast gene expression regulation growth inhibition human human cell malignant neoplastic disease mouse nonhuman osteoblast protein expression signal transduction tumor growth animal biosynthesis cell line drug antagonism drug effect fluorescent antibody technique ionizing radiation metabolism phosphorylation physiology Western blotting Murinae Animals Blotting, Western Cell Line Cell Proliferation DNA Damage Doxorubicin Fatty Acid Synthetase Complex Fatty Acids Fluorescent Antibody Technique Humans Hydroxyurea Mice Oncogene Protein p21(ras) Osteoblasts Phosphorylation Radiation, Ionizing Tumor Suppressor Protein p53 Zeng L. Wu G.-Z. Goh K.J. Lee Y.M. Ng C.C. You A.B. Wang J. Jia D. Hao A. Yu Q. Li B. Saturated fatty acids modulate cell response to DNA damage: Implication for their role in tumorigenesis |
description |
10.1371/journal.pone.0002329 |
author2 |
PHYSIOLOGY |
author_facet |
PHYSIOLOGY Zeng L. Wu G.-Z. Goh K.J. Lee Y.M. Ng C.C. You A.B. Wang J. Jia D. Hao A. Yu Q. Li B. |
format |
Article |
author |
Zeng L. Wu G.-Z. Goh K.J. Lee Y.M. Ng C.C. You A.B. Wang J. Jia D. Hao A. Yu Q. Li B. |
author_sort |
Zeng L. |
title |
Saturated fatty acids modulate cell response to DNA damage: Implication for their role in tumorigenesis |
title_short |
Saturated fatty acids modulate cell response to DNA damage: Implication for their role in tumorigenesis |
title_full |
Saturated fatty acids modulate cell response to DNA damage: Implication for their role in tumorigenesis |
title_fullStr |
Saturated fatty acids modulate cell response to DNA damage: Implication for their role in tumorigenesis |
title_full_unstemmed |
Saturated fatty acids modulate cell response to DNA damage: Implication for their role in tumorigenesis |
title_sort |
saturated fatty acids modulate cell response to dna damage: implication for their role in tumorigenesis |
publishDate |
2019 |
url |
https://scholarbank.nus.edu.sg/handle/10635/161854 |
_version_ |
1821194051707207680 |