Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway

10.1371/journal.ppat.1007298

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Main Authors:	Ye W., Chew M., Hou J., Lai F., Leopold S.J., Loo H.L., Ghose A., Dutta A.K., Chen Q., Ooi E.E., White N.J., Dondorp A.M., Preiser P., Chen J.
Other Authors:	MEDICINE
Format:	Article
Published:	2019
Subjects:	bilirubin CD69 antigen creatinine gamma interferon granulysin interferon induced helicase C domain containing protein 1 interleukin 2 receptor alpha lectin receptor lysosome associated membrane protein 1 natural killer cell receptor NKG2A natural killer cell receptor NKG2D IFIH1 protein, human adult Article cell heterogeneity confocal microscopy controlled study cytotoxicity discriminant analysis erythrocyte female flow cytometry gel electrophoresis gene expression hematocrit human human cell hypoglycemia immune response immunoassay malaria male membrane microparticle microarray analysis natural killer T cell parasitemia peripheral blood mononuclear cell Plasmodium falciparum protein expression respiratory failure reverse transcription RNA isolation signal transduction systolic blood pressure Western blotting antagonists and inhibitors cell culture CRISPR Cas system cytoplasm genetics immunology isolation and purification lymphocyte activation malaria falciparum metabolism natural killer cell parasitology Cell-Derived Microparticles Cells, Cultured CRISPR-Cas Systems Cytoplasm Erythrocytes Humans Interferon-Induced Helicase, IFIH1 Killer Cells, Natural Lymphocyte Activation Malaria, Falciparum
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161879
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1618792024-05-08T09:52:07Z Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway Ye W. Chew M. Hou J. Lai F. Leopold S.J. Loo H.L. Ghose A. Dutta A.K. Chen Q. Ooi E.E. White N.J. Dondorp A.M. Preiser P. Chen J. MEDICINE MICROBIOLOGY AND IMMUNOLOGY DUKE-NUS MEDICAL SCHOOL BIOLOGICAL SCIENCES bilirubin CD69 antigen creatinine gamma interferon granulysin interferon induced helicase C domain containing protein 1 interleukin 2 receptor alpha lectin receptor lysosome associated membrane protein 1 natural killer cell receptor NKG2A natural killer cell receptor NKG2D IFIH1 protein, human interferon induced helicase C domain containing protein 1 adult Article cell heterogeneity confocal microscopy controlled study cytotoxicity discriminant analysis erythrocyte female flow cytometry gel electrophoresis gene expression hematocrit human human cell hypoglycemia immune response immunoassay malaria male membrane microparticle microarray analysis natural killer T cell parasitemia peripheral blood mononuclear cell Plasmodium falciparum protein expression respiratory failure reverse transcription RNA isolation signal transduction systolic blood pressure Western blotting antagonists and inhibitors cell culture CRISPR Cas system cytoplasm erythrocyte genetics immunology isolation and purification lymphocyte activation malaria falciparum membrane microparticle metabolism natural killer cell parasitology Cell-Derived Microparticles Cells, Cultured CRISPR-Cas Systems Cytoplasm Erythrocytes Humans Interferon-Induced Helicase, IFIH1 Killer Cells, Natural Lymphocyte Activation Malaria, Falciparum Plasmodium falciparum 10.1371/journal.ppat.1007298 PLoS Pathogens 14 10 e1007298 2019-11-08T06:41:37Z 2019-11-08T06:41:37Z 2018 Article Ye W., Chew M., Hou J., Lai F., Leopold S.J., Loo H.L., Ghose A., Dutta A.K., Chen Q., Ooi E.E., White N.J., Dondorp A.M., Preiser P., Chen J. (2018). Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway. PLoS Pathogens 14 (10) : e1007298. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.ppat.1007298 15537366 https://scholarbank.nus.edu.sg/handle/10635/161879 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	bilirubin CD69 antigen creatinine gamma interferon granulysin interferon induced helicase C domain containing protein 1 interleukin 2 receptor alpha lectin receptor lysosome associated membrane protein 1 natural killer cell receptor NKG2A natural killer cell receptor NKG2D IFIH1 protein, human interferon induced helicase C domain containing protein 1 adult Article cell heterogeneity confocal microscopy controlled study cytotoxicity discriminant analysis erythrocyte female flow cytometry gel electrophoresis gene expression hematocrit human human cell hypoglycemia immune response immunoassay malaria male membrane microparticle microarray analysis natural killer T cell parasitemia peripheral blood mononuclear cell Plasmodium falciparum protein expression respiratory failure reverse transcription RNA isolation signal transduction systolic blood pressure Western blotting antagonists and inhibitors cell culture CRISPR Cas system cytoplasm erythrocyte genetics immunology isolation and purification lymphocyte activation malaria falciparum membrane microparticle metabolism natural killer cell parasitology Cell-Derived Microparticles Cells, Cultured CRISPR-Cas Systems Cytoplasm Erythrocytes Humans Interferon-Induced Helicase, IFIH1 Killer Cells, Natural Lymphocyte Activation Malaria, Falciparum Plasmodium falciparum
spellingShingle	bilirubin CD69 antigen creatinine gamma interferon granulysin interferon induced helicase C domain containing protein 1 interleukin 2 receptor alpha lectin receptor lysosome associated membrane protein 1 natural killer cell receptor NKG2A natural killer cell receptor NKG2D IFIH1 protein, human interferon induced helicase C domain containing protein 1 adult Article cell heterogeneity confocal microscopy controlled study cytotoxicity discriminant analysis erythrocyte female flow cytometry gel electrophoresis gene expression hematocrit human human cell hypoglycemia immune response immunoassay malaria male membrane microparticle microarray analysis natural killer T cell parasitemia peripheral blood mononuclear cell Plasmodium falciparum protein expression respiratory failure reverse transcription RNA isolation signal transduction systolic blood pressure Western blotting antagonists and inhibitors cell culture CRISPR Cas system cytoplasm erythrocyte genetics immunology isolation and purification lymphocyte activation malaria falciparum membrane microparticle metabolism natural killer cell parasitology Cell-Derived Microparticles Cells, Cultured CRISPR-Cas Systems Cytoplasm Erythrocytes Humans Interferon-Induced Helicase, IFIH1 Killer Cells, Natural Lymphocyte Activation Malaria, Falciparum Plasmodium falciparum Ye W. Chew M. Hou J. Lai F. Leopold S.J. Loo H.L. Ghose A. Dutta A.K. Chen Q. Ooi E.E. White N.J. Dondorp A.M. Preiser P. Chen J. Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway
description	10.1371/journal.ppat.1007298
author2	MEDICINE
author_facet	MEDICINE Ye W. Chew M. Hou J. Lai F. Leopold S.J. Loo H.L. Ghose A. Dutta A.K. Chen Q. Ooi E.E. White N.J. Dondorp A.M. Preiser P. Chen J.
format	Article
author	Ye W. Chew M. Hou J. Lai F. Leopold S.J. Loo H.L. Ghose A. Dutta A.K. Chen Q. Ooi E.E. White N.J. Dondorp A.M. Preiser P. Chen J.
author_sort	Ye W.
title	Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway
title_short	Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway
title_full	Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway
title_fullStr	Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway
title_full_unstemmed	Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway
title_sort	microvesicles from malaria-infected red blood cells activate natural killer cells via mda5 pathway
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161879
_version_	1800913823640584192

Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway

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