Structure-Based Statistical Mechanical Model Accounts for the Causality and Energetics of Allosteric Communication

• Main Authors: Guarnera E., Berezovsky I.N.
• Other Authors: BIOLOGICAL SCIENCES
• Format: Article
• Published: 2019
• Subjects: allosterism; Article; controlled study; energy transfer; feasibility study; ligand binding; limit of quantitation; oligomerization; protein conformation; protein engineering; protein localization; thermodynamics; allosteric site; amino acid sequence; chemical model; chemistry; computer simulation; enzyme activation; molecular genetics; molecular model; statistical model; structure activity relation; ultrastructure; enzyme; protein binding; Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Computer Simulation; Energy Transfer; Enzyme Activation; Enzymes; Models, Chemical; Models, Molecular; Models, Statistical; Molecular Sequence Data; Protein Binding; Protein Conformation; Structure-Activity Relationship; Thermodynamics
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161920
• Institution: National University of Singapore

10.1371/journal.pcbi.1004678