Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease

• Main Authors: Mäkinen V.-P., Civelek M., Meng Q., Zhang B., Zhu J., Levian C., Huan T., Segrè A.V., Ghosh S., Vivar J., Nikpay M., Stewart A.F.R., Nelson C.P., Willenborg C., Erdmann J., Blakenberg S., O'Donnell C.J., März W., Laaksonen R., Epstein S.E., Kathiresan S., Shah S.H., Hazen S.L., Reilly M.P., Lusis A.J., Samani N.J., Schunkert H., Quertermous T., McPherson R., Yang X., Assimes T.L.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2019
• Subjects: lactoylglutathione lyase; small interfering RNA; article; controlled study; coronary artery disease; endothelium cell; gene; gene control; gene expression; gene interaction; gene regulatory network; genetic association; genomics; glyoxalase I gene; human; human cell; human genome; major clinical study; peptidylprolyl isomerase I gene; quantitative trait locus; single nucleotide polymorphism; animal; gene expression regulation; genetic predisposition; genetics; meta analysis; mouse; pathology; signal transduction; Animals; Coronary Artery Disease; Gene Expression Regulation; Gene Regulatory Networks; Genetic Predisposition to Disease; Genome-Wide Association Study; Genomics; Humans; Mice; Signal Transduction
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161947
• Institution: National University of Singapore

10.1371/journal.pgen.1004502