Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease

10.1371/journal.pgen.1004502

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Main Authors: M�kinen V.-P., Civelek M., Meng Q., Zhang B., Zhu J., Levian C., Huan T., Segr� A.V., Ghosh S., Vivar J., Nikpay M., Stewart A.F.R., Nelson C.P., Willenborg C., Erdmann J., Blakenberg S., O'Donnell C.J., M�rz W., Laaksonen R., Epstein S.E., Kathiresan S., Shah S.H., Hazen S.L., Reilly M.P., Lusis A.J., Samani N.J., Schunkert H., Quertermous T., McPherson R., Yang X., Assimes T.L.
Other Authors: DUKE-NUS MEDICAL SCHOOL
Format: Article
Published: 2019
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/161947
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spelling sg-nus-scholar.10635-1619472023-09-21T08:25:16Z Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease M�kinen V.-P. Civelek M. Meng Q. Zhang B. Zhu J. Levian C. Huan T. Segr� A.V. Ghosh S. Vivar J. Nikpay M. Stewart A.F.R. Nelson C.P. Willenborg C. Erdmann J. Blakenberg S. O'Donnell C.J. M�rz W. Laaksonen R. Epstein S.E. Kathiresan S. Shah S.H. Hazen S.L. Reilly M.P. Lusis A.J. Samani N.J. Schunkert H. Quertermous T. McPherson R. Yang X. Assimes T.L. DUKE-NUS MEDICAL SCHOOL lactoylglutathione lyase small interfering RNA article controlled study coronary artery disease endothelium cell gene gene control gene expression gene interaction gene regulatory network genetic association genomics glyoxalase I gene human human cell human genome major clinical study peptidylprolyl isomerase I gene quantitative trait locus single nucleotide polymorphism animal coronary artery disease gene expression regulation gene regulatory network genetic predisposition genetics genomics meta analysis mouse pathology signal transduction Animals Coronary Artery Disease Gene Expression Regulation Gene Regulatory Networks Genetic Predisposition to Disease Genome-Wide Association Study Genomics Humans Mice Signal Transduction 10.1371/journal.pgen.1004502 PLoS Genetics 10 7 e1004502 2019-11-08T08:49:45Z 2019-11-08T08:49:45Z 2014 Article M�kinen V.-P., Civelek M., Meng Q., Zhang B., Zhu J., Levian C., Huan T., Segr� A.V., Ghosh S., Vivar J., Nikpay M., Stewart A.F.R., Nelson C.P., Willenborg C., Erdmann J., Blakenberg S., O'Donnell C.J., M�rz W., Laaksonen R., Epstein S.E., Kathiresan S., Shah S.H., Hazen S.L., Reilly M.P., Lusis A.J., Samani N.J., Schunkert H., Quertermous T., McPherson R., Yang X., Assimes T.L. (2014). Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease. PLoS Genetics 10 (7) : e1004502. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pgen.1004502 15537390 https://scholarbank.nus.edu.sg/handle/10635/161947 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic lactoylglutathione lyase
small interfering RNA
article
controlled study
coronary artery disease
endothelium cell
gene
gene control
gene expression
gene interaction
gene regulatory network
genetic association
genomics
glyoxalase I gene
human
human cell
human genome
major clinical study
peptidylprolyl isomerase I gene
quantitative trait locus
single nucleotide polymorphism
animal
coronary artery disease
gene expression regulation
gene regulatory network
genetic predisposition
genetics
genomics
meta analysis
mouse
pathology
signal transduction
Animals
Coronary Artery Disease
Gene Expression Regulation
Gene Regulatory Networks
Genetic Predisposition to Disease
Genome-Wide Association Study
Genomics
Humans
Mice
Signal Transduction
spellingShingle lactoylglutathione lyase
small interfering RNA
article
controlled study
coronary artery disease
endothelium cell
gene
gene control
gene expression
gene interaction
gene regulatory network
genetic association
genomics
glyoxalase I gene
human
human cell
human genome
major clinical study
peptidylprolyl isomerase I gene
quantitative trait locus
single nucleotide polymorphism
animal
coronary artery disease
gene expression regulation
gene regulatory network
genetic predisposition
genetics
genomics
meta analysis
mouse
pathology
signal transduction
Animals
Coronary Artery Disease
Gene Expression Regulation
Gene Regulatory Networks
Genetic Predisposition to Disease
Genome-Wide Association Study
Genomics
Humans
Mice
Signal Transduction
M�kinen V.-P.
Civelek M.
Meng Q.
Zhang B.
Zhu J.
Levian C.
Huan T.
Segr� A.V.
Ghosh S.
Vivar J.
Nikpay M.
Stewart A.F.R.
Nelson C.P.
Willenborg C.
Erdmann J.
Blakenberg S.
O'Donnell C.J.
M�rz W.
Laaksonen R.
Epstein S.E.
Kathiresan S.
Shah S.H.
Hazen S.L.
Reilly M.P.
Lusis A.J.
Samani N.J.
Schunkert H.
Quertermous T.
McPherson R.
Yang X.
Assimes T.L.
Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease
description 10.1371/journal.pgen.1004502
author2 DUKE-NUS MEDICAL SCHOOL
author_facet DUKE-NUS MEDICAL SCHOOL
M�kinen V.-P.
Civelek M.
Meng Q.
Zhang B.
Zhu J.
Levian C.
Huan T.
Segr� A.V.
Ghosh S.
Vivar J.
Nikpay M.
Stewart A.F.R.
Nelson C.P.
Willenborg C.
Erdmann J.
Blakenberg S.
O'Donnell C.J.
M�rz W.
Laaksonen R.
Epstein S.E.
Kathiresan S.
Shah S.H.
Hazen S.L.
Reilly M.P.
Lusis A.J.
Samani N.J.
Schunkert H.
Quertermous T.
McPherson R.
Yang X.
Assimes T.L.
format Article
author M�kinen V.-P.
Civelek M.
Meng Q.
Zhang B.
Zhu J.
Levian C.
Huan T.
Segr� A.V.
Ghosh S.
Vivar J.
Nikpay M.
Stewart A.F.R.
Nelson C.P.
Willenborg C.
Erdmann J.
Blakenberg S.
O'Donnell C.J.
M�rz W.
Laaksonen R.
Epstein S.E.
Kathiresan S.
Shah S.H.
Hazen S.L.
Reilly M.P.
Lusis A.J.
Samani N.J.
Schunkert H.
Quertermous T.
McPherson R.
Yang X.
Assimes T.L.
author_sort M�kinen V.-P.
title Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease
title_short Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease
title_full Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease
title_fullStr Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease
title_full_unstemmed Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease
title_sort integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease
publishDate 2019
url https://scholarbank.nus.edu.sg/handle/10635/161947
_version_ 1778169228039290880