Inhibition of enterovirus 71 (EV-71) infections by a novel antiviral peptide derived from EV-71 capsid protein VP1

10.1371/journal.pone.0034589

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Main Authors:	Tan C.W., Chan Y.F., Sim K.M., Tan E.L., Poh C.L.
Other Authors:	PAEDIATRICS
Format:	Article
Published:	2019
Subjects:	antivirus agent arginine lysine protein VP1 SP40 peptide SP40X peptide unclassified drug alanine capsid protein oligopeptide amino acid substitution animal cell antiviral activity article cancer cell concentration response controlled study Coxsackie virus A drug mechanism drug specificity Enterovirus 71 Enterovirus infection female genotype human human cell IC 50 in vitro study nonhuman nucleotide sequence Poliomyelitis virus 1 rhabdomyosarcoma structure activity relation virus attachment amino acid sequence animal cell proliferation cell strain HT29 cell survival Cercopithecus chemical structure chemistry drug effect Enterovirus genetics growth, development and aging HeLa cell molecular genetics peptide library protein conformation protein secondary structure sequence homology synthesis tumor cell line Vero cell virology Human enterovirus 71 Human poliovirus 1 Miridae Alanine Amino Acid Sequence Amino Acid Substitution Animals Antiviral Agents Capsid Proteins Cell Line, Tumor Cell Proliferation Cell Survival Cercopithecus aethiops Enterovirus A, Human Enterovirus Infections HeLa Cells HT29 Cells Humans Inhibitory Concentration 50 Models, Molecular Molecular Sequence Data Oligopeptides Peptide Library Protein Conformation Protein Structure, Secondary Sequence Homology, Amino Acid Vero Cells
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161985
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1619852024-11-09T06:19:46Z Inhibition of enterovirus 71 (EV-71) infections by a novel antiviral peptide derived from EV-71 capsid protein VP1 Tan C.W. Chan Y.F. Sim K.M. Tan E.L. Poh C.L. PAEDIATRICS antivirus agent arginine lysine protein VP1 SP40 peptide SP40X peptide unclassified drug alanine capsid protein oligopeptide amino acid substitution animal cell antiviral activity article cancer cell concentration response controlled study Coxsackie virus A drug mechanism drug specificity Enterovirus 71 Enterovirus infection female genotype human human cell IC 50 in vitro study nonhuman nucleotide sequence Poliomyelitis virus 1 rhabdomyosarcoma structure activity relation virus attachment amino acid sequence animal cell proliferation cell strain HT29 cell survival Cercopithecus chemical structure chemistry drug effect Enterovirus Enterovirus infection genetics growth, development and aging HeLa cell molecular genetics peptide library protein conformation protein secondary structure sequence homology synthesis tumor cell line Vero cell virology Human enterovirus 71 Human poliovirus 1 Miridae Alanine Amino Acid Sequence Amino Acid Substitution Animals Antiviral Agents Capsid Proteins Cell Line, Tumor Cell Proliferation Cell Survival Cercopithecus aethiops Enterovirus A, Human Enterovirus Infections HeLa Cells HT29 Cells Humans Inhibitory Concentration 50 Models, Molecular Molecular Sequence Data Oligopeptides Peptide Library Protein Conformation Protein Structure, Secondary Sequence Homology, Amino Acid Vero Cells 10.1371/journal.pone.0034589 PLoS ONE 7 5 e34589 2019-11-11T06:39:58Z 2019-11-11T06:39:58Z 2012 Article Tan C.W., Chan Y.F., Sim K.M., Tan E.L., Poh C.L. (2012). Inhibition of enterovirus 71 (EV-71) infections by a novel antiviral peptide derived from EV-71 capsid protein VP1. PLoS ONE 7 (5) : e34589. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0034589 19326203 https://scholarbank.nus.edu.sg/handle/10635/161985 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	antivirus agent arginine lysine protein VP1 SP40 peptide SP40X peptide unclassified drug alanine capsid protein oligopeptide amino acid substitution animal cell antiviral activity article cancer cell concentration response controlled study Coxsackie virus A drug mechanism drug specificity Enterovirus 71 Enterovirus infection female genotype human human cell IC 50 in vitro study nonhuman nucleotide sequence Poliomyelitis virus 1 rhabdomyosarcoma structure activity relation virus attachment amino acid sequence animal cell proliferation cell strain HT29 cell survival Cercopithecus chemical structure chemistry drug effect Enterovirus Enterovirus infection genetics growth, development and aging HeLa cell molecular genetics peptide library protein conformation protein secondary structure sequence homology synthesis tumor cell line Vero cell virology Human enterovirus 71 Human poliovirus 1 Miridae Alanine Amino Acid Sequence Amino Acid Substitution Animals Antiviral Agents Capsid Proteins Cell Line, Tumor Cell Proliferation Cell Survival Cercopithecus aethiops Enterovirus A, Human Enterovirus Infections HeLa Cells HT29 Cells Humans Inhibitory Concentration 50 Models, Molecular Molecular Sequence Data Oligopeptides Peptide Library Protein Conformation Protein Structure, Secondary Sequence Homology, Amino Acid Vero Cells
spellingShingle	antivirus agent arginine lysine protein VP1 SP40 peptide SP40X peptide unclassified drug alanine capsid protein oligopeptide amino acid substitution animal cell antiviral activity article cancer cell concentration response controlled study Coxsackie virus A drug mechanism drug specificity Enterovirus 71 Enterovirus infection female genotype human human cell IC 50 in vitro study nonhuman nucleotide sequence Poliomyelitis virus 1 rhabdomyosarcoma structure activity relation virus attachment amino acid sequence animal cell proliferation cell strain HT29 cell survival Cercopithecus chemical structure chemistry drug effect Enterovirus Enterovirus infection genetics growth, development and aging HeLa cell molecular genetics peptide library protein conformation protein secondary structure sequence homology synthesis tumor cell line Vero cell virology Human enterovirus 71 Human poliovirus 1 Miridae Alanine Amino Acid Sequence Amino Acid Substitution Animals Antiviral Agents Capsid Proteins Cell Line, Tumor Cell Proliferation Cell Survival Cercopithecus aethiops Enterovirus A, Human Enterovirus Infections HeLa Cells HT29 Cells Humans Inhibitory Concentration 50 Models, Molecular Molecular Sequence Data Oligopeptides Peptide Library Protein Conformation Protein Structure, Secondary Sequence Homology, Amino Acid Vero Cells Tan C.W. Chan Y.F. Sim K.M. Tan E.L. Poh C.L. Inhibition of enterovirus 71 (EV-71) infections by a novel antiviral peptide derived from EV-71 capsid protein VP1
description	10.1371/journal.pone.0034589
author2	PAEDIATRICS
author_facet	PAEDIATRICS Tan C.W. Chan Y.F. Sim K.M. Tan E.L. Poh C.L.
format	Article
author	Tan C.W. Chan Y.F. Sim K.M. Tan E.L. Poh C.L.
author_sort	Tan C.W.
title	Inhibition of enterovirus 71 (EV-71) infections by a novel antiviral peptide derived from EV-71 capsid protein VP1
title_short	Inhibition of enterovirus 71 (EV-71) infections by a novel antiviral peptide derived from EV-71 capsid protein VP1
title_full	Inhibition of enterovirus 71 (EV-71) infections by a novel antiviral peptide derived from EV-71 capsid protein VP1
title_fullStr	Inhibition of enterovirus 71 (EV-71) infections by a novel antiviral peptide derived from EV-71 capsid protein VP1
title_full_unstemmed	Inhibition of enterovirus 71 (EV-71) infections by a novel antiviral peptide derived from EV-71 capsid protein VP1
title_sort	inhibition of enterovirus 71 (ev-71) infections by a novel antiviral peptide derived from ev-71 capsid protein vp1
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161985
_version_	1821194979592110080

Inhibition of enterovirus 71 (EV-71) infections by a novel antiviral peptide derived from EV-71 capsid protein VP1

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