Genome wide expression profiling reveals suppression of host defence responses during colonisation by neisseria meningitides but not N. lactamica

10.1371/journal.pone.0026130

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Main Authors:	Wong H.E.E., Li M.-S., Kroll J.S., Hibberd M.L., Langford P.R.
Other Authors:	SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
Format:	Article
Published:	2019
Subjects:	bacterial protein complement component C1s transcriptome tumor necrosis factor alpha autacoid cytokine article bacterial colonization bacterial genome bacterial secretion system controlled study disease association down regulation energy yield evolutionary adaptation gene expression profiling gene expression regulation gene induction genetic association genetic selection host resistance human human cell immunomodulation long term exposure lung alveolus epithelium meningococcosis microarray analysis monolayer culture Neisseria lactamica Neisseria meningitidis nonhuman nucleotide sequence species differentiation upregulation adaptation bronchus cell line cytology cytoplasm energy metabolism epithelium cell genetics genomics immunity immunology metabolism microbial viability microbiology physiology secretion species difference time Bacteria (microorganisms) Adaptation, Physiological Bacterial Proteins Bronchi Cell Line Complement C1s Cytokines Cytoplasm Down-Regulation Energy Metabolism Epithelial Cells Gene Expression Regulation Genomics Humans Immunity Inflammation Mediators Microbial Viability Species Specificity Time Factors Transcriptome Tumor Necrosis Factor-alpha
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/162027
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1620272020-11-18T02:11:27Z Genome wide expression profiling reveals suppression of host defence responses during colonisation by neisseria meningitides but not N. lactamica Wong H.E.E. Li M.-S. Kroll J.S. Hibberd M.L. Langford P.R. SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH bacterial protein complement component C1s transcriptome tumor necrosis factor alpha autacoid bacterial protein complement component C1s cytokine transcriptome tumor necrosis factor alpha article bacterial colonization bacterial genome bacterial secretion system controlled study disease association down regulation energy yield evolutionary adaptation gene expression profiling gene expression regulation gene induction genetic association genetic selection host resistance human human cell immunomodulation long term exposure lung alveolus epithelium meningococcosis microarray analysis monolayer culture Neisseria lactamica Neisseria meningitidis nonhuman nucleotide sequence species differentiation upregulation adaptation bronchus cell line cytology cytoplasm energy metabolism epithelium cell genetics genomics immunity immunology metabolism microbial viability microbiology physiology secretion species difference time Bacteria (microorganisms) Neisseria lactamica Neisseria meningitidis Adaptation, Physiological Bacterial Proteins Bronchi Cell Line Complement C1s Cytokines Cytoplasm Down-Regulation Energy Metabolism Epithelial Cells Gene Expression Regulation Genomics Humans Immunity Inflammation Mediators Microbial Viability Neisseria lactamica Neisseria meningitidis Species Specificity Time Factors Transcriptome Tumor Necrosis Factor-alpha 10.1371/journal.pone.0026130 PLoS ONE 6 10 e26130 2019-11-11T08:37:05Z 2019-11-11T08:37:05Z 2011 Article Wong H.E.E., Li M.-S., Kroll J.S., Hibberd M.L., Langford P.R. (2011). Genome wide expression profiling reveals suppression of host defence responses during colonisation by neisseria meningitides but not N. lactamica. PLoS ONE 6 (10) : e26130. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0026130 19326203 https://scholarbank.nus.edu.sg/handle/10635/162027 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	bacterial protein complement component C1s transcriptome tumor necrosis factor alpha autacoid bacterial protein complement component C1s cytokine transcriptome tumor necrosis factor alpha article bacterial colonization bacterial genome bacterial secretion system controlled study disease association down regulation energy yield evolutionary adaptation gene expression profiling gene expression regulation gene induction genetic association genetic selection host resistance human human cell immunomodulation long term exposure lung alveolus epithelium meningococcosis microarray analysis monolayer culture Neisseria lactamica Neisseria meningitidis nonhuman nucleotide sequence species differentiation upregulation adaptation bronchus cell line cytology cytoplasm energy metabolism epithelium cell genetics genomics immunity immunology metabolism microbial viability microbiology physiology secretion species difference time Bacteria (microorganisms) Neisseria lactamica Neisseria meningitidis Adaptation, Physiological Bacterial Proteins Bronchi Cell Line Complement C1s Cytokines Cytoplasm Down-Regulation Energy Metabolism Epithelial Cells Gene Expression Regulation Genomics Humans Immunity Inflammation Mediators Microbial Viability Neisseria lactamica Neisseria meningitidis Species Specificity Time Factors Transcriptome Tumor Necrosis Factor-alpha
spellingShingle	bacterial protein complement component C1s transcriptome tumor necrosis factor alpha autacoid bacterial protein complement component C1s cytokine transcriptome tumor necrosis factor alpha article bacterial colonization bacterial genome bacterial secretion system controlled study disease association down regulation energy yield evolutionary adaptation gene expression profiling gene expression regulation gene induction genetic association genetic selection host resistance human human cell immunomodulation long term exposure lung alveolus epithelium meningococcosis microarray analysis monolayer culture Neisseria lactamica Neisseria meningitidis nonhuman nucleotide sequence species differentiation upregulation adaptation bronchus cell line cytology cytoplasm energy metabolism epithelium cell genetics genomics immunity immunology metabolism microbial viability microbiology physiology secretion species difference time Bacteria (microorganisms) Neisseria lactamica Neisseria meningitidis Adaptation, Physiological Bacterial Proteins Bronchi Cell Line Complement C1s Cytokines Cytoplasm Down-Regulation Energy Metabolism Epithelial Cells Gene Expression Regulation Genomics Humans Immunity Inflammation Mediators Microbial Viability Neisseria lactamica Neisseria meningitidis Species Specificity Time Factors Transcriptome Tumor Necrosis Factor-alpha Wong H.E.E. Li M.-S. Kroll J.S. Hibberd M.L. Langford P.R. Genome wide expression profiling reveals suppression of host defence responses during colonisation by neisseria meningitides but not N. lactamica
description	10.1371/journal.pone.0026130
author2	SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
author_facet	SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH Wong H.E.E. Li M.-S. Kroll J.S. Hibberd M.L. Langford P.R.
format	Article
author	Wong H.E.E. Li M.-S. Kroll J.S. Hibberd M.L. Langford P.R.
author_sort	Wong H.E.E.
title	Genome wide expression profiling reveals suppression of host defence responses during colonisation by neisseria meningitides but not N. lactamica
title_short	Genome wide expression profiling reveals suppression of host defence responses during colonisation by neisseria meningitides but not N. lactamica
title_full	Genome wide expression profiling reveals suppression of host defence responses during colonisation by neisseria meningitides but not N. lactamica
title_fullStr	Genome wide expression profiling reveals suppression of host defence responses during colonisation by neisseria meningitides but not N. lactamica
title_full_unstemmed	Genome wide expression profiling reveals suppression of host defence responses during colonisation by neisseria meningitides but not N. lactamica
title_sort	genome wide expression profiling reveals suppression of host defence responses during colonisation by neisseria meningitides but not n. lactamica
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/162027
_version_	1686108559509553152

Genome wide expression profiling reveals suppression of host defence responses during colonisation by neisseria meningitides but not N. lactamica

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