Genome wide expression profiling reveals suppression of host defence responses during colonisation by neisseria meningitides but not N. lactamica

• Main Authors: Wong H.E.E., Li M.-S., Kroll J.S., Hibberd M.L., Langford P.R.
• Other Authors: SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
• Format: Article
• Published: 2019
• Subjects: bacterial protein; complement component C1s; transcriptome; tumor necrosis factor alpha; autacoid; cytokine; article; bacterial colonization; bacterial genome; bacterial secretion system; controlled study; disease association; down regulation; energy yield; evolutionary adaptation; gene expression profiling; gene expression regulation; gene induction; genetic association; genetic selection; host resistance; human; human cell; immunomodulation; long term exposure; lung alveolus epithelium; meningococcosis; microarray analysis; monolayer culture; Neisseria lactamica; Neisseria meningitidis; nonhuman; nucleotide sequence; species differentiation; upregulation; adaptation; bronchus; cell line; cytology; cytoplasm; energy metabolism; epithelium cell; genetics; genomics; immunity; immunology; metabolism; microbial viability; microbiology; physiology; secretion; species difference; time; Bacteria (microorganisms); Adaptation, Physiological; Bacterial Proteins; Bronchi; Cell Line; Complement C1s; Cytokines; Cytoplasm; Down-Regulation; Energy Metabolism; Epithelial Cells; Gene Expression Regulation; Genomics; Humans; Immunity; Inflammation Mediators; Microbial Viability; Species Specificity; Time Factors; Transcriptome; Tumor Necrosis Factor-alpha
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/162027
• Institution: National University of Singapore

10.1371/journal.pone.0026130