Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission

• Main Authors: Pompon J., Manuel M., Ng G.K., Wong B., Shan C., Manokaran G., Soto-Acosta R., Bradrick S.S., Ooi E.E., Missé D., Shi P.-Y., Garcia-Blanco M.A.
• Other Authors: DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
• Format: Article
• Published: Public Library of Science 2020
• Subjects: animal cell; Article; controlled study; dengue; down regulation; female; gene disruption; gene expression; immune response; infection rate; mosquito; next generation sequencing; nonhuman; Northern blotting; sequence analysis; virus isolation; virus titration; virus transmission; Aedes; animal; Dengue virus; genetics; human; immunology; insect vector; metabolism; physiology; salivary gland; transmission; virology; virus replication; virus RNA; Animals; Dengue; Dengue Virus; Humans; Insect Vectors; RNA, Viral; Salivary Glands; Virus Replication
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165374
• Institution: National University of Singapore

10.1371/journal.ppat.1006535