Xist RNA repeat E is essential for ASH2L recruitment to the inactive X and regulates histone modifications and escape gene expression

• Main Authors: Yue M., Ogawa A., Yamada N., Charles Richard J.L., Barski A., Ogawa Y.
• Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
• Format: Article
• Published: Public Library of Science 2020
• Subjects: long non coding RNA Xist; long untranslated RNA; membrane protein; protein ASH2L; unclassified drug; Ash2l protein, mouse; DNA binding protein; nuclear protein; transcription factor; XIST non-coding RNA; animal cell; Article; chromatin immunoprecipitation; controlled study; endothelium cell; enzyme localization; epigenetics; exon; female; gene control; gene expression; gene inactivation; half life time; histone modification; immunoprecipitation; mouse; nonhuman; protein depletion; protein RNA binding; quantitative analysis; reverse transcription polymerase chain reaction; upregulation; animal; biosynthesis; cell differentiation; embryonic stem cell; gene deletion; gene expression regulation; gene silencing; genetic transcription; genetics; histone code; metabolism; X chromosome; X chromosome inactivation; Animals; Cell Differentiation; DNA-Binding Proteins; Embryonic Stem Cells; Exons; Gene Deletion; Gene Expression Regulation; Gene Silencing; Histone Code; Mice; Nuclear Proteins; RNA, Long Noncoding; Transcription Factors; Transcription, Genetic; X Chromosome; X Chromosome Inactivation
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165375
• Institution: National University of Singapore

10.1371/journal.pgen.1006890