Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint

10.1371/journal.pgen.1006310

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Main Authors:	Diril M.K., Bisteau X., Kitagawa M., Caldez M.J., Wee S., Gunaratne J., Lee S.H., Kaldis P.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	Public Library of Science 2020
Subjects:	cell enzyme cyclin dependent kinase 1 MPS1 protein okadaic acid phosphoprotein phosphatase 2A phosphotransferase protein Mad1 unclassified drug greatwall protein, mouse microtubule associated protein phosphoprotein phosphatase 2 Ppp2r2a protein, mouse protein serine threonine kinase Ttk protein, mouse adult animal cell animal experiment animal tissue Article cell proliferation cellular distribution centromere chromosome segregation controlled study cytokinesis embryo embryo development enzyme activity enzyme localization enzyme phosphorylation essential gene fibroblast gene function gene inactivation gene loss in vitro study knockout gene knockout mouse M phase cell cycle checkpoint Mastl gene microtubule mitosis inhibition mouse nonhuman protein dephosphorylation protein determination protein localization protein phosphorylation animal genetics kinetochore metabolism mitosis phosphorylation spindle apparatus Animals CDC2 Protein Kinase Chromosome Segregation Cytokinesis Kinetochores M Phase Cell Cycle Checkpoints Mice Mice, Knockout Microtubule-Associated Proteins Microtubules Mitosis Phosphorylation Protein Phosphatase 2 Protein-Serine-Threonine Kinases Spindle Apparatus
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/165381
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1653812023-10-31T20:50:10Z Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint Diril M.K. Bisteau X. Kitagawa M. Caldez M.J. Wee S. Gunaratne J. Lee S.H. Kaldis P. DUKE-NUS MEDICAL SCHOOL cell enzyme cyclin dependent kinase 1 MPS1 protein okadaic acid phosphoprotein phosphatase 2A phosphotransferase protein Mad1 unclassified drug cyclin dependent kinase 1 greatwall protein, mouse microtubule associated protein phosphoprotein phosphatase 2 Ppp2r2a protein, mouse protein serine threonine kinase Ttk protein, mouse adult animal cell animal experiment animal tissue Article cell proliferation cellular distribution centromere chromosome segregation controlled study cytokinesis embryo embryo development enzyme activity enzyme localization enzyme phosphorylation essential gene fibroblast gene function gene inactivation gene loss in vitro study knockout gene knockout mouse M phase cell cycle checkpoint Mastl gene microtubule mitosis inhibition mouse nonhuman protein dephosphorylation protein determination protein localization protein phosphorylation animal genetics kinetochore M phase cell cycle checkpoint metabolism mitosis phosphorylation spindle apparatus Animals CDC2 Protein Kinase Chromosome Segregation Cytokinesis Kinetochores M Phase Cell Cycle Checkpoints Mice Mice, Knockout Microtubule-Associated Proteins Microtubules Mitosis Phosphorylation Protein Phosphatase 2 Protein-Serine-Threonine Kinases Spindle Apparatus 10.1371/journal.pgen.1006310 PLoS Genetics 12 9 e1006310 2020-03-13T05:23:08Z 2020-03-13T05:23:08Z 2016 Article Diril M.K., Bisteau X., Kitagawa M., Caldez M.J., Wee S., Gunaratne J., Lee S.H., Kaldis P. (2016). Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint. PLoS Genetics 12 (9) : e1006310. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pgen.1006310 15537390 https://scholarbank.nus.edu.sg/handle/10635/165381 Public Library of Science Unpaywall 20200320
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	cell enzyme cyclin dependent kinase 1 MPS1 protein okadaic acid phosphoprotein phosphatase 2A phosphotransferase protein Mad1 unclassified drug cyclin dependent kinase 1 greatwall protein, mouse microtubule associated protein phosphoprotein phosphatase 2 Ppp2r2a protein, mouse protein serine threonine kinase Ttk protein, mouse adult animal cell animal experiment animal tissue Article cell proliferation cellular distribution centromere chromosome segregation controlled study cytokinesis embryo embryo development enzyme activity enzyme localization enzyme phosphorylation essential gene fibroblast gene function gene inactivation gene loss in vitro study knockout gene knockout mouse M phase cell cycle checkpoint Mastl gene microtubule mitosis inhibition mouse nonhuman protein dephosphorylation protein determination protein localization protein phosphorylation animal genetics kinetochore M phase cell cycle checkpoint metabolism mitosis phosphorylation spindle apparatus Animals CDC2 Protein Kinase Chromosome Segregation Cytokinesis Kinetochores M Phase Cell Cycle Checkpoints Mice Mice, Knockout Microtubule-Associated Proteins Microtubules Mitosis Phosphorylation Protein Phosphatase 2 Protein-Serine-Threonine Kinases Spindle Apparatus
spellingShingle	cell enzyme cyclin dependent kinase 1 MPS1 protein okadaic acid phosphoprotein phosphatase 2A phosphotransferase protein Mad1 unclassified drug cyclin dependent kinase 1 greatwall protein, mouse microtubule associated protein phosphoprotein phosphatase 2 Ppp2r2a protein, mouse protein serine threonine kinase Ttk protein, mouse adult animal cell animal experiment animal tissue Article cell proliferation cellular distribution centromere chromosome segregation controlled study cytokinesis embryo embryo development enzyme activity enzyme localization enzyme phosphorylation essential gene fibroblast gene function gene inactivation gene loss in vitro study knockout gene knockout mouse M phase cell cycle checkpoint Mastl gene microtubule mitosis inhibition mouse nonhuman protein dephosphorylation protein determination protein localization protein phosphorylation animal genetics kinetochore M phase cell cycle checkpoint metabolism mitosis phosphorylation spindle apparatus Animals CDC2 Protein Kinase Chromosome Segregation Cytokinesis Kinetochores M Phase Cell Cycle Checkpoints Mice Mice, Knockout Microtubule-Associated Proteins Microtubules Mitosis Phosphorylation Protein Phosphatase 2 Protein-Serine-Threonine Kinases Spindle Apparatus Diril M.K. Bisteau X. Kitagawa M. Caldez M.J. Wee S. Gunaratne J. Lee S.H. Kaldis P. Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint
description	10.1371/journal.pgen.1006310
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Diril M.K. Bisteau X. Kitagawa M. Caldez M.J. Wee S. Gunaratne J. Lee S.H. Kaldis P.
format	Article
author	Diril M.K. Bisteau X. Kitagawa M. Caldez M.J. Wee S. Gunaratne J. Lee S.H. Kaldis P.
author_sort	Diril M.K.
title	Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint
title_short	Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint
title_full	Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint
title_fullStr	Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint
title_full_unstemmed	Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint
title_sort	loss of the greatwall kinase weakens the spindle assembly checkpoint
publisher	Public Library of Science
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/165381
_version_	1781791927030513664

Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint

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