Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint

• المؤلفون الرئيسيون: Diril M.K., Bisteau X., Kitagawa M., Caldez M.J., Wee S., Gunaratne J., Lee S.H., Kaldis P.
• مؤلفون آخرون: DUKE-NUS MEDICAL SCHOOL
• التنسيق: مقال
• منشور في: Public Library of Science 2020
• الموضوعات: cell enzyme; cyclin dependent kinase 1; MPS1 protein; okadaic acid; phosphoprotein phosphatase 2A; phosphotransferase; protein Mad1; unclassified drug; greatwall protein, mouse; microtubule associated protein; phosphoprotein phosphatase 2; Ppp2r2a protein, mouse; protein serine threonine kinase; Ttk protein, mouse; adult; animal cell; animal experiment; animal tissue; Article; cell proliferation; cellular distribution; centromere; chromosome segregation; controlled study; cytokinesis; embryo; embryo development; enzyme activity; enzyme localization; enzyme phosphorylation; essential gene; fibroblast; gene function; gene inactivation; gene loss; in vitro study; knockout gene; knockout mouse; M phase cell cycle checkpoint; Mastl gene; microtubule; mitosis inhibition; mouse; nonhuman; protein dephosphorylation; protein determination; protein localization; protein phosphorylation; animal; genetics; kinetochore; metabolism; mitosis; phosphorylation; spindle apparatus; Animals; CDC2 Protein Kinase; Chromosome Segregation; Cytokinesis; Kinetochores; M Phase Cell Cycle Checkpoints; Mice; Mice, Knockout; Microtubule-Associated Proteins; Microtubules; Mitosis; Phosphorylation; Protein Phosphatase 2; Protein-Serine-Threonine Kinases; Spindle Apparatus
• الوصول للمادة أونلاين: https://scholarbank.nus.edu.sg/handle/10635/165381

10.1371/journal.pgen.1006310