Modelling the evolution and spread of HIV immune escape mutants

• Main Authors: Fryer H.R., Frater J., Duda A., Roberts M.G., Phillips R.E., McLean A.R.
• Format: Article
• Published: Public Library of Science 2020
• Subjects: article; cytotoxic T lymphocyte; disease transmission; escape behavior; evolution; genetic heterogeneity; host; human; Human immunodeficiency virus; immunity; mathematical model; nonhuman; population; prevalence; virus mutant; genetics; Human immunodeficiency virus 1; Human immunodeficiency virus infection; immunology; mutation; pathology; phylogeny; theoretical model; epitope; Gag protein; Nef protein; reverse transcriptase, Human immunodeficiency virus 1; RNA directed DNA polymerase; Biological Evolution; Epitopes, T-Lymphocyte; gag Gene Products, Human Immunodeficiency Virus; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Models, Theoretical; Mutation; nef Gene Products, Human Immunodeficiency Virus; Phylogeny; T-Lymphocytes, Cytotoxic
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165415
• Institution: National University of Singapore

10.1371/journal.ppat.1001196