The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription

The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription

10.1371/journal.ppat.1001038

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Bibliographic Details
Main Authors:	Morin B., Coutard B., Lelke M., Ferron F., Kerber R., Jamal S., Frangeul A., Baronti C., Charrel R., de Lamballerie X., Vonrhein C., Lescar J., Bricogne G., Günther S., Canard B.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	Public Library of Science 2020
Subjects:	arenavirus L protein messenger RNA unclassified drug virus protein amino terminal sequence Arenavirus article controlled study crystal structure enzyme active site enzyme activity Lymphocytic choriomeningitis virus mutagenesis mutational analysis nonhuman protein cross linking replicon RNA binding RNA replication RNA transcription virus characterization Bunyaviridae Catalytic Domain Crystallization Crystallography, X-Ray Endonucleases Endoribonucleases Models, Molecular Mutagenesis Orthomyxoviridae Protein Structure, Tertiary RNA, Messenger RNA, Viral Transcription, Genetic Arenaviridae
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/165417
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Institution:	National University of Singapore

Description
Summary:	10.1371/journal.ppat.1001038