IFN-γ mediates the rejection of haematopoietic stem cells in IFN-γR1-deficient hosts

• Main Authors: Rottman M., Soudais C., Vogt G., Renia L., Emile J.-F., Decaluwe H., Gaillard J.-L., Casanova J.-L.
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: Public Library of Science 2020
• Subjects: gamma interferon; gamma interferon receptor 1; parvovirus vector; gamma interferon receptor; hybrid protein; interferon receptor; interleukin 12; monoclonal antibody; animal cell; animal experiment; animal model; animal tissue; article; controlled study; disease association; graft rejection; hematopoietic stem cell transplantation; human; human cell; in vivo study; mouse; mycobacteriosis; Mycobacterium bovis; nonhuman; protein expression; Adeno associated virus; animal; blood; bone marrow transplantation; C57BL mouse; female; gene vector; genetic predisposition; genetics; germfree animal; hematopoietic stem cell; immunology; male; metabolism; microbiology; mouse mutant; pathogenicity; pathophysiology; physiology; radiation chimera; tuberculosis; Animals; Antibodies, Monoclonal; Bone Marrow Transplantation; Dependovirus; Female; Genetic Predisposition to Disease; Genetic Vectors; Graft Rejection; Hematopoietic Stem Cells; Interferon-gamma; Interleukin-12; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Radiation Chimera; Receptors, Interferon; Recombinant Fusion Proteins; Specific Pathogen-Free Organisms; Tuberculosis
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165426
• Institution: National University of Singapore

10.1371/journal.pmed.0050026