Basal immunoglobulin signaling actively maintains developmental stage in immature B cells

• Main Authors: Tze L.E., Schram B.R., Lam K.-P., Hogquist K.A., Hippen K.L., Liu J., Shinton S.A., Otipoby K.L., Rodine P.R., Vegoe A.L., Kraus M., Hardy R.R., Schlissel M.S., Rajewsky K., Behrens T.W.
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Conference or Workshop Item
• Published: Public Library of Science 2020
• Subjects: androstane derivative; cre recombinase; green fluorescent protein; herbimycin A; immunoglobulin; immunoglobulin heavy chain; immunoglobulin light chain; immunoglobulin M; pharmacology; phosphatidylinositol 3 kinase inhibitor; protein tyrosine kinase inhibitor; wortmannin; allele; animal; animal cell; article; B lymphocyte; bone marrow cell; cell culture; cell maturation; conference paper; controlled study; cytology; developmental stage; drug effect; gene rearrangement; genetics; immunology; incubation time; mouse; mouse mutant; nonhuman; nucleotide sequence; physiology; plasticity; signal transduction; transgenic mouse; Androstadienes; Animals; B-Lymphocytes; Bone Marrow Cells; Cells, Cultured; drug effects; Gene Rearrangement; Gene Rearrangement, B-Lymphocyte; Green Fluorescent Proteins; Immunoglobulin Heavy Chains; Immunoglobulin Light Chains; Immunoglobulin M; Immunoglobulins; Mice; Mice, Knockout; Mice, Transgenic; Signal Transduction
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165427
• Institution: National University of Singapore

10.1371/journal.pbio.0030082